Domains within Homo sapiens protein MORN3_HUMAN (Q6PF18)

MORN repeat-containing protein 3

Alternative representations: 1 /

Protein length240 aa
Source databaseUniProt
Identifiers MORN3_HUMAN, Q6PF18, ENSP00000347486.3, ENSP00000347486, ENSP00000493930.1, ENSP00000493930, Q86YQ9
Source gene ENSG00000139714
Alternative splicing MORN3_HUMAN, A0A024RBS9_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

MORN3_HUMAN is shown as MORN3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for MORN3

Protein MORN3_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05014Amyotrophic lateral sclerosis

KEGG orthologous groups

KONameDescription
K19530JPHjunctophilin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Methylation2
Phosphorylation1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein MORN3.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000347486 in eggNOG.

OGTaxonomic classDescription
LCOG4642All organisms (root)junctophilin,radial spoke head protein 1,amyotrophic lateral sclerosis 2 protein
KOG0231Eukaryota (superkingdom)junctophilin,radial spoke head protein 1,amyotrophic lateral sclerosis 2 protein
HV8PNMetazoa (kingdom)MORN
94KQTChordata (phylum)MORN
5QDPQSarcopterygii (superclass)MORN
8ZKD4Mammalia (class)MORN
4R3B2Euarchontoglires (superorder)MORN
4ZXQYPrimates (order)MORN
98ESMHaplorrhini (suborder)MORN
BVAA9Simiiformes (infraorder)MORN
9EHKTCatarrhini (parvorder)MORN
H4WCWBilateria (clade)MORN
9G84KVertebrata (clade)MORN
7JEGBOpisthokonta (clade)MORN
FX0HQHominoidea (superfamily)MORN
5N6VXHominidae (family)MORN
5Y7DZHomininae (subfamily)MORN

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: