Domains within Homo sapiens protein GPRL1_HUMAN (Q6UWM5)

GLIPR1-like protein 1

Alternative representations: 1 /

Protein length242 aa
Source databaseUniProt
Identifiers GPRL1_HUMAN, Q6UWM5, ENSP00000367967.4, ENSP00000367967, Q96L06
Source gene ENSG00000173401
Alternative splicing GPRL1_HUMAN, Q6UWM5-2, A0A0D9SG94_HUMAN, H0YIW6_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

GPRL1_HUMAN is shown as GLIPR1L1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for GLIPR1L1

Protein GPRL1_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map00520Amino sugar and nucleotide sugar metabolism iPath3
map04075Plant hormone signal transduction
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

KONameDescription
K13449PR1pathogenesis-related protein 1
K19919CRISP1_2_3cysteine-rich secretory protein 1/2/3
K24836PI15, CRISP8peptidase inhibitor 15

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000367967 in eggNOG.

OGTaxonomic classDescription
LCOG2340All organisms (root)pathogenesis-related protein 1,cysteine-rich secretory protein LCCL domain-containing,glioma pathogenesis-related protein 1
KOG3017Eukaryota (superkingdom)pathogenesis-related protein 1,cysteine-rich secretory protein LCCL domain-containing,glioma pathogenesis-related protein 1
HV2VZMetazoa (kingdom)peptidase inhibitor 15,peptidase inhibitor 16,glioma pathogenesis-related protein 1
93EEAChordata (phylum)glioma pathogenesis-related protein 1
5QB6JSarcopterygii (superclass)glioma pathogenesis-related protein 1
8Z72AMammalia (class)glioma pathogenesis-related protein 1
4R6KCEuarchontoglires (superorder)glioma pathogenesis-related protein 1
5039JPrimates (order)glioma pathogenesis-related protein 1
98HPXHaplorrhini (suborder)glioma pathogenesis-related protein 1
BV4TYSimiiformes (infraorder)glioma pathogenesis-related protein 1
9EXBUCatarrhini (parvorder)glioma pathogenesis-related protein 1
H4D3XBilateria (clade)peptidase inhibitor 15,peptidase inhibitor 16,glioma pathogenesis-related protein 1
7KBNSOpisthokonta (clade)cysteine-rich secretory protein 1/2/3,glioma pathogenesis-related protein 1,glioma pathogenesis-related protein 2
9FXQYVertebrata (clade)glioma pathogenesis-related protein 1
FXECSHominoidea (superfamily)glioma pathogenesis-related protein 1
5N9Z1Hominidae (family)glioma pathogenesis-related protein 1
5XTNGHomininae (subfamily)glioma pathogenesis-related protein 1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: