Domains within Homo sapiens protein OLFM4_HUMAN (Q6UX06)

Olfactomedin-4

Alternative representations: 1 /

Protein length510 aa
Source databaseUniProt
Identifiers OLFM4_HUMAN, Q6UX06, ENSP00000219022.2, ENSP00000219022, O95362, Q5VWG0, Q86T22, A0A024QZ95_HUMAN, A0A024QZ95
Source gene ENSG00000102837

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

OLFM4_HUMAN is shown as OLFM4 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for OLFM4

Protein OLFM4_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04080Neuroactive ligand-receptor interaction

KEGG orthologous groups

KONameDescription
K25448OLFML1_3olfactomedin-like protein 1/3

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 10 PTMs annotated in this protein:

PTMCount
Phosphorylation8
Nitrosylation1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein OLFM4.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000219022 in eggNOG.

OGTaxonomic classDescription
LKOG3545All organisms (root)olfactomedin-like protein 1/3,olfactomedin-like protein 2,olfactomedin-4
5JTDBEukaryota (superkingdom)olfactomedin-4,ubiquilin-like protein
HSQYWMetazoa (kingdom)olfactomedin-4,ubiquilin-like protein
94VD9Chordata (phylum)olfactomedin-4,ubiquilin-like protein
5QN81Sarcopterygii (superclass)olfactomedin-4,ubiquilin-like protein
8ZA92Mammalia (class)olfactomedin-4,ubiquilin-like protein
4RKS6Euarchontoglires (superorder)olfactomedin-4
4ZVVKPrimates (order)olfactomedin-4
98NHCHaplorrhini (suborder)olfactomedin-4
BUZ0CSimiiformes (infraorder)olfactomedin-4
9EGIXCatarrhini (parvorder)olfactomedin-4
7GHEYOpisthokonta (clade)olfactomedin-4,ubiquilin-like protein
9FV4PVertebrata (clade)olfactomedin-4,ubiquilin-like protein
H67NUBilateria (clade)olfactomedin-4,ubiquilin-like protein
FXEPUHominoidea (superfamily)olfactomedin-4
5MYHZHominidae (family)olfactomedin-4
5Y3BJHomininae (subfamily)olfactomedin-4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: