Domains within Homo sapiens protein CEA20_HUMAN (Q6UY09)

Carcinoembryonic antigen-related cell adhesion molecule 20

Alternative representations: 1 /

Protein length596 aa
Source databaseUniProt
Identifiers CEA20_HUMAN, Q6UY09, ENSP00000481937.1, ENSP00000481937, A0A087WXE1, A0A087WYH6, A0A087WYM6, A0A087WZX4, A0A087X155, A7LFK7, A7LFK8, A7LFK9, A7LFL0
Source gene ENSG00000273777
Alternative splicing Q6UY09-5, Q6UY09-4, Q6UY09-3, CEA20_HUMAN, Q6UY09-2, A0A087X0T2_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

CEA20_HUMAN is shown as CEACAM20 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CEACAM20

Protein CEA20_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05169Epstein-Barr virus infection
map04722Neurotrophin signaling pathway
map05166Human T-cell leukemia virus 1 infection
map04625C-type lectin receptor signaling pathway

KEGG orthologous groups

KONameDescription
K10999CESAcellulose synthase A [EC:2.4.1.12]
K06867K06867uncharacterized protein
K06499CEACAM, CD66carcinoembryonic antigen-related cell adhesion molecule

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000481937 in eggNOG.

OGTaxonomic classDescription
LCOG0666All organisms (root)uncharacterized protein,Mce-associated membrane protein,cellulose synthase A [EC:2.4.1.12]
KOG0504Eukaryota (superkingdom)cellulose synthase A [EC:2.4.1.12],beta-mannan synthase [EC:2.4.1.32],uncharacterized protein
HUPK9Metazoa (kingdom)carcinoembryonic antigen-related cell adhesion molecule,NF-kappa-B inhibitor alpha,nuclear factor NF-kappa-B p105 subunit
9407NChordata (phylum)B-cell CLL/lymphoma 3 protein,carcinoembryonic antigen-related cell adhesion molecule,pregnancy specific beta-1-glycoprotein
5QSI8Sarcopterygii (superclass)carcinoembryonic antigen-related cell adhesion molecule
8Z7NSMammalia (class)carcinoembryonic antigen-related cell adhesion molecule
4RMJPEuarchontoglires (superorder)carcinoembryonic antigen-related cell adhesion molecule
4ZQW6Primates (order)carcinoembryonic antigen-related cell adhesion molecule
9856UHaplorrhini (suborder)carcinoembryonic antigen-related cell adhesion molecule
BUYZTSimiiformes (infraorder)carcinoembryonic antigen-related cell adhesion molecule
9EKW3Catarrhini (parvorder)carcinoembryonic antigen-related cell adhesion molecule
7MMYUOpisthokonta (clade)carcinoembryonic antigen-related cell adhesion molecule,ankyrin repeat domain-containing protein 50,NF-kappa-B inhibitor alpha
9G4Q9Vertebrata (clade)B-cell CLL/lymphoma 3 protein,carcinoembryonic antigen-related cell adhesion molecule,pregnancy specific beta-1-glycoprotein
H58U6Bilateria (clade)carcinoembryonic antigen-related cell adhesion molecule,NF-kappa-B inhibitor alpha,ankyrin repeat domain-containing protein 6
FX978Hominoidea (superfamily)carcinoembryonic antigen-related cell adhesion molecule
5NAT0Hominidae (family)carcinoembryonic antigen-related cell adhesion molecule

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: