Domains within Mus musculus protein A2ACM0_MOUSE (A2ACM0)

Regulatory-associated protein of mTOR

Alternative representations: 1 /

Protein length1335 aa
Source databaseUniProt
Identifiers A2ACM0_MOUSE, A2ACM0, ENSMUSP00000026671.6, ENSMUSP00000026671, Q6ZPU3_MOUSE, Q6ZPU3, A4FUW1_MOUSE, A4FUW1
Source gene ENSMUSG00000025583
Alternative splicing E9PXZ5_MOUSE, A2ACM0_MOUSE, F7CN67_MOUSE, ENSMUSP00000124886.1, F7BQS0_MOUSE, F7B6I3_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

A2ACM0_MOUSE is shown as Rptor in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Rptor

Protein A2ACM0_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04211Longevity regulating pathway

KEGG orthologous groups

KONameDescription
K07204RAPTORregulatory associated protein of mTOR

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 45 PTMs annotated in this protein:

PTMCount
Phosphorylation35
Ubiquitination9
Nitrosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein 4932417H02Rik.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000026671 in eggNOG.

OGTaxonomic classDescription
LKOG1517All organisms (root)regulatory associated protein of mTOR,ER lumen protein retaining receptor
KOG1517Eukaryota (superkingdom)regulatory associated protein of mTOR,ER lumen protein retaining receptor
HWACKMetazoa (kingdom)regulatory associated protein of mTOR
93MFKChordata (phylum)regulatory associated protein of mTOR
5QMI6Sarcopterygii (superclass)regulatory associated protein of mTOR
8Z6P8Mammalia (class)regulatory associated protein of mTOR
4RNCCEuarchontoglires (superorder)regulatory associated protein of mTOR
AICSIRodentia (order)regulatory associated protein of mTOR
8D46ZMyomorpha (suborder)regulatory associated protein of mTOR
9FU35Vertebrata (clade)regulatory associated protein of mTOR
H52VTBilateria (clade)regulatory associated protein of mTOR
7JI4UOpisthokonta (clade)regulatory associated protein of mTOR
CQ2Y2Muridae (family)regulatory associated protein of mTOR
AE8EQMurinae (subfamily)regulatory associated protein of mTOR
5PQZJMus (genus)regulatory associated protein of mTOR
HEDDXMus (subgenus)regulatory associated protein of mTOR

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: