Domains within Homo sapiens protein RN207_HUMAN (Q6ZRF8)

RING finger protein 207

Alternative representations: 1 /

Protein length634 aa
Source databaseUniProt
Identifiers RN207_HUMAN, Q6ZRF8, ENSP00000367173.4, ENSP00000367173, A2VCM8, B4DFR6, Q5TGS6, Q6ZS63, Q96MP2
Source gene ENSG00000158286

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

RN207_HUMAN is shown as RNF207 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RNF207

Protein RN207_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04120Ubiquitin mediated proteolysis

KEGG orthologous groups

KONameDescription
K06712BTN, CD277butyrophilin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein RNF207.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000367173 in eggNOG.

OGTaxonomic classDescription
LKOG2177All organisms (root)butyrophilin,tripartite motif-containing protein 2/3,deltex [EC:2.3.2.27]
KOG2177Eukaryota (superkingdom)butyrophilin,tripartite motif-containing protein 2/3,deltex [EC:2.3.2.27]
HT6NKMetazoa (kingdom)zf-B_box,zf-C3HC4,zf-RING_UBOX
94TPYChordata (phylum)zf-B_box,zf-C3HC4,zf-RING_UBOX
5QE6BSarcopterygii (superclass)zf-B_box,zf-C3HC4,zf-RING_UBOX
8Z3XSMammalia (class)zf-B_box,zf-C3HC4,DUF3583
4RN2REuarchontoglires (superorder)zf-B_box,zf-C3HC4,DUF3583
4ZMAUPrimates (order)zf-C3HC4,zf-B_box,DUF3583
98FCSHaplorrhini (suborder)zf-B_box,zf-C3HC4,DUF3583
BV55BSimiiformes (infraorder)zf-C3HC4,zf-B_box,DUF3583
9F18ECatarrhini (parvorder)zf-C3HC4,zf-B_box,DUF3583
9FMJQVertebrata (clade)zf-B_box,zf-C3HC4,zf-RING_UBOX
H3D3EBilateria (clade)zf-B_box,zf-C3HC4,zf-RING_UBOX
7GJCEOpisthokonta (clade)zf-B_box,zf-C3HC4,zf-RING_UBOX
FX9XIHominoidea (superfamily)zf-C3HC4,zf-B_box
5N9W9Hominidae (family)zf-C3HC4,zf-B_box
5XYTTHomininae (subfamily)zf-C3HC4,zf-B_box

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: