Domains within Drosophila melanogaster protein RL40_DROME (P18101)

Ubiquitin-60S ribosomal protein L40

Alternative representations: 1 /

Protein length128 aa
Source databaseUniProt
Identifiers RL40_DROME, P18101, FBPP0077159, FBPP0306837, P68198, Q0E8I1, Q9VKW6, Q9VQX7, Q9VZL4, B4NRW4_DROSI, B4NRW4, A0A1W4UQN2_DROFC, A0A1W4UQN2, Q5MIQ5_AEDAL, Q5MIQ5, B6DDR1_ANODA, B6DDR1, Q06DG5_ANOFN, Q06DG5, A0A182S1N6, Q6XIQ1_DROYA, Q6XIQ1, A0A182VB73_ANOME, A0A182VB73, Q7Q3K7_ANOGA, Q7Q3K7, A0A182IKK6_9DIPT, A0A182IKK6, A0A084VP31_ANOSI, A0A084VP31, Q7KF35_AEDAE, Q7KF35, A0A182SV28_9DIPT, A0A182SV28, A0A182QY10_9DIPT, A0A182QY10, Q7JYK1_DROME, Q7JYK1, B4N0N3_DROWI, B4N0N3, A0A182UHQ4_9DIPT, A0A182UHQ4, B0W5N8_CULQU, B0W5N8, A0A182MAZ1_9DIPT, A0A182MAZ1, A0A1Y9GKL0_ANOAR, A0A1Y9GKL0, A0A1I8NRI3_STOCA, A0A1I8NRI3, A0A1I8M438_MUSDO, A0A1I8M438, A0A1B0FP56_GLOMM, A0A1B0FP56, A0A240PP72_9DIPT, A0A240PP72, W8BCX2_CERCA, W8BCX2, B4MDC8_DROVI, B4MDC8, C6ZQZ8_OCHTR, C6ZQZ8, A0A1W4XWD7_AGRPL, A0A1W4XWD7, Q95NR0_ANOST, Q95NR0, A0A1A9W0F3_9MUSC, A0A1A9W0F3, A0A1Y9G8A6_ANOAL, A0A1Y9G8A6, A0A1A9ZJ33_GLOPL, A0A1A9ZJ33, U5EX98_9DIPT, U5EX98, B4GQQ7_DROPE, B4GQQ7, A0A1L8EHW7_HAEIR, A0A1L8EHW7, A0A1Q3FUD8_CULTA, A0A1Q3FUD8, Q29NP1_DROPS, Q29NP1, A0A0A1WXV4_ZEUCU, A0A0A1WXV4, B3N3Q0_DROER, B3N3Q0, B4JD38_DROGR, B4JD38, T1E7V7_ANOAQ, T1E7V7, A0A1B0B5R6_9MUSC, A0A1B0B5R6, T1D5B9_9DIPT, T1D5B9, A0A240PN80_9DIPT, A0A240PN80, A0A1A9UMV8_GLOAU, A0A1A9UMV8, B3MLU8_DROAN, B3MLU8, A0A1A9XH84_GLOFF, A0A1A9XH84, B4KFP9_DROMO, B4KFP9
Source gene FBgn0003941

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

RL40_DROME is shown as RpL40 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RpL40

Protein RL40_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05171Coronavirus disease - COVID-19

KEGG orthologous groups

KONameDescription
K02927RP-L40e, RPL40, UBA52ubiquitin-large subunit ribosomal protein L40e

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 84 PTMs annotated in this protein:

PTMCount
Acetylation27
Phosphorylation21
Ubiquitination21
Nitrosylation6
Methylation3
SUMOylation3
Isopeptide bond3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein RpL40.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0306837 in eggNOG.

OGTaxonomic classDescription
LKOG0003All organisms (root)ubiquitin-large subunit ribosomal protein L40e,RNA polymerase I-specific transcription initiation factor RRN7,ubiquitin-small subunit ribosomal protein S27Ae
EIGRJEndopterygota (cohort)ubiquitin-large subunit ribosomal protein L40e
KOG0003Eukaryota (superkingdom)ubiquitin-large subunit ribosomal protein L40e,RNA polymerase I-specific transcription initiation factor RRN7,ubiquitin-small subunit ribosomal protein S27Ae
HSSEBMetazoa (kingdom)ubiquitin-large subunit ribosomal protein L40e,KxDL motif-containing protein 1,ubiquitin-small subunit ribosomal protein S27Ae
HIHS9Arthropoda (phylum)ubiquitin-large subunit ribosomal protein L40e
85TCMHexapoda (subphylum)ubiquitin-large subunit ribosomal protein L40e
AHNTQNeoptera (infraclass)ubiquitin-large subunit ribosomal protein L40e
ANEJPDiptera (order)ubiquitin-large subunit ribosomal protein L40e
H67SFBilateria (clade)ubiquitin-large subunit ribosomal protein L40e,KxDL motif-containing protein 1,ubiquitin-small subunit ribosomal protein S27Ae
7HNRCOpisthokonta (clade)ubiquitin-large subunit ribosomal protein L40e,RNA polymerase I-specific transcription initiation factor RRN7,KxDL motif-containing protein 1
EGYMUDrosophila (genus)ubiquitin-large subunit ribosomal protein L40e
50CS6Sophophora (subgenus)ubiquitin-large subunit ribosomal protein L40e

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: