Domains within Drosophila melanogaster protein A0A0B4KGT8_DROME (A0A0B4KGT8)

Cheerio, isoform M

Alternative representations: 1 /

Protein length2429 aa
Source databaseUniProt
Identifiers A0A0B4KGT8_DROME, A0A0B4KGT8, FBPP0308015, Q7KSF4_DROME, Q7KSF4
Source gene FBgn0014141
Alternative splicing FBpp0308014, B7Z0L2_DROME, FBpp0292427, FBpp0288454, A0A0B4KGT8_DROME, FLNA_DROME, A0A0B4KHN1_DROME, A0A0B4KGB3_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

A0A0B4KGT8_DROME is shown as cher in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for cher

Protein A0A0B4KGT8_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04510Focal adhesion

KEGG orthologous groups

KONameDescription
K04437FLNAfilamin-A

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0308015 in eggNOG.

OGTaxonomic classDescription
EJAIWEndopterygota (cohort)filamin,tensin
FV1XVmelanogaster group (species group)filamin
FE0YNmelanogaster subgroup (species subgroup)filamin
LKOG0518All organisms (root)filamin,neuron navigator 3,neuron navigator 2 [EC:5.6.2.4]
KOG0518Eukaryota (superkingdom)filamin,neuron navigator 3,neuron navigator 2 [EC:5.6.2.4]
HTNKNMetazoa (kingdom)filamin,tensin
HI3ZBArthropoda (phylum)filamin,tensin
85IA3Hexapoda (subphylum)filamin,tensin
AH7YNNeoptera (infraclass)filamin,tensin
AP1WMDiptera (order)filamin
7JV2IOpisthokonta (clade)filamin,tensin
H60DKBilateria (clade)filamin,tensin
EH3K5Drosophila (genus)filamin
50E9YSophophora (subgenus)filamin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: