Domains within Drosophila melanogaster protein Q9W0C5_DROME (Q9W0C5)

ATP binding cassette subfamily B member 7, isoform A

Alternative representations: 1 /

Protein length743 aa
Source databaseUniProt
Identifiers Q9W0C5_DROME, Q9W0C5, FBPP0072637, Q7KVA9_DROME, Q7KVA9
Source gene FBgn0035244
Alternative splicing Q9W0C5_DROME, Q7KVB1_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

Q9W0C5_DROME is shown as ABCB7 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ABCB7

Protein Q9W0C5_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02010ABC transporters

KEGG orthologous groups

KONameDescription
K05662ABCB7, ATMATP-binding cassette, subfamily B (MDR/TAP), member 7
K24821atm1, pexAATP-binding cassette, subfamily B, heavy metal transporter

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 7 PTMs annotated in this protein:

PTMCount
Acetylation4
Phosphorylation3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ABCB7.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0072637 in eggNOG.

OGTaxonomic classDescription
LCOG5265All organisms (root)ATP-binding cassette, subfamily B, heavy metal transporter,ATP-binding cassette, subfamily B (MDR/TAP), member 7,ATP-binding cassette, subfamily B (MDR/TAP), member 6
EJ5ZZEndopterygota (cohort)ATP-binding cassette, subfamily B (MDR/TAP), member 7
FUUP5melanogaster group (species group)ATP-binding cassette, subfamily B (MDR/TAP), member 7
FDXA5melanogaster subgroup (species subgroup)ATP-binding cassette, subfamily B (MDR/TAP), member 7
KOG0057Eukaryota (superkingdom)ATP-binding cassette, subfamily B (MDR/TAP), member 7,ATP-binding cassette, subfamily B, bacterial
HVN1YMetazoa (kingdom)ATP-binding cassette, subfamily B (MDR/TAP), member 7
HIQVVArthropoda (phylum)ATP-binding cassette, subfamily B (MDR/TAP), member 7
867J0Hexapoda (subphylum)ATP-binding cassette, subfamily B (MDR/TAP), member 7
AHJTFNeoptera (infraclass)ATP-binding cassette, subfamily B (MDR/TAP), member 7
ANMG4Diptera (order)ATP-binding cassette, subfamily B (MDR/TAP), member 7
7M5QPOpisthokonta (clade)ATP-binding cassette, subfamily B (MDR/TAP), member 7
H6MJQBilateria (clade)ATP-binding cassette, subfamily B (MDR/TAP), member 7
EH5JTDrosophila (genus)ATP-binding cassette, subfamily B (MDR/TAP), member 7
50CFNSophophora (subgenus)ATP-binding cassette, subfamily B (MDR/TAP), member 7

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: