Domains within Drosophila melanogaster protein AGO3_DROME (Q7PLK0)

Protein argonaute-3

Alternative representations: 1 /

Protein length867 aa
Source databaseUniProt
Identifiers AGO3_DROME, Q7PLK0, FBPP0289159, FBPP0289158, FBPP0289160, A4GND8, A4GUJ7, A7YFW6, B6IDV1, B7FNN2, K7WKR9, K7XHY4
Source gene FBgn0250816
Alternative splicing AGO3_DROME, Q7PLK0-2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

AGO3_DROME is shown as AGO3 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for AGO3

Protein AGO3_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04320Dorso-ventral axis formation

KEGG orthologous groups

KONameDescription
K02156AUB, PIWIaubergine

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 9 PTMs annotated in this protein:

PTMCount
Phosphorylation5
Ubiquitination3
Methylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AGO3.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0289159 in eggNOG.

OGTaxonomic classDescription
LKOG1042All organisms (root)aubergine,galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-],DNA-directed RNA polymerase III subunit RPC4
EIU34Endopterygota (cohort)aubergine
FV6QZmelanogaster group (species group)aubergine
KOG1042Eukaryota (superkingdom)aubergine,galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-],DNA-directed RNA polymerase III subunit RPC4
HT3IBMetazoa (kingdom)aubergine,galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-],DNA-directed RNA polymerase III subunit RPC4
HI78GArthropoda (phylum)aubergine
868H5Hexapoda (subphylum)aubergine
AH3EINeoptera (infraclass)aubergine
ANBFTDiptera (order)aubergine
H6TADBilateria (clade)aubergine,galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-],DNA-directed RNA polymerase III subunit RPC4
7JWT9Opisthokonta (clade)aubergine,galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-],DNA-directed RNA polymerase III subunit RPC4
EGW3PDrosophila (genus)aubergine
50NRCSophophora (subgenus)aubergine

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: