Domains within Anopheles gambiae protein STAT_ANOGA (Q7QDU4)

Signal transducer and transcription activator

Alternative representations: 1 /

Protein length722 aa
Source databaseUniProt
Identifiers O97164, STAT_ANOGA, Q7QDU4

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

STAT_ANOGA is shown as Stat in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Stat

Protein STAT_ANOGA is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04630JAK-STAT signaling pathway
map05203Viral carcinogenesis

KEGG orthologous groups

KONameDescription
K11224STAT5Bsignal transducer and activator of transcription 5B

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 18 PTMs annotated in this protein:

PTMCount
Phosphorylation11
Ubiquitination4
Acetylation2
Methylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Stat.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7165.Q7QDU4 in eggNOG.

OGTaxonomic classDescription
LKOG3667All organisms (root)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 1,signal transducer and activator of transcription 3
EIZN9Endopterygota (cohort)signal transducer and activator of transcription 5B
KOG3667Eukaryota (superkingdom)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 1,signal transducer and activator of transcription 3
HU8P6Metazoa (kingdom)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 3,signal transducer and activator of transcription 1
HIS7RArthropoda (phylum)signal transducer and activator of transcription 5B
86GH6Hexapoda (subphylum)signal transducer and activator of transcription 5B
AHJ9CNeoptera (infraclass)signal transducer and activator of transcription 5B
AP0VRDiptera (order)signal transducer and activator of transcription 5B
G9RGDCulicomorpha (infraorder)signal transducer and activator of transcription 5B
H4SJ1Bilateria (clade)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 3,signal transducer and activator of transcription 1
7MSZPOpisthokonta (clade)signal transducer and activator of transcription 5B,signal transducer and activator of transcription 3,signal transducer and activator of transcription 1
9MAMRCulicidae (family)signal transducer and activator of transcription 5B
G2Z35Anopheles (genus)signal transducer and activator of transcription 5B
E6SNDCellia (subgenus)signal transducer and activator of transcription 5B

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: