Domains within Homo sapiens protein ARMC9_HUMAN (Q7Z3E5)

LisH domain-containing protein ARMC9

Alternative representations: 1 /

Protein length818 aa
Source databaseUniProt
Identifiers ARMC9_HUMAN, Q7Z3E5, ENSP00000484804.1, ENSP00000484804, ENSP00000484241.1, ENSP00000484241, A0A087X1I8, Q53TI3, Q6P162, Q7L594, Q86WG2, Q96JF9, Q9H9R8
Source gene ENSG00000135931
Alternative splicing ENSP00000258417.5, C9JW07_HUMAN, ARMC9_HUMAN, H7C2P6_HUMAN, H7BZY2_HUMAN, H7C3U7_HUMAN, C9J535_HUMAN, H7BZA2_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ARMC9_HUMAN is shown as ARMC9 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ARMC9

Protein ARMC9_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map00533Glycosaminoglycan biosynthesis - keratan sulfate

KEGG orthologous groups

KONameDescription
K07820B3GALT2beta-1,3-galactosyltransferase 2 [EC:2.4.1.86] iPath3
K22864ARMC9LisH domain-containing protein ARMC9
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000484804 in eggNOG.

OGTaxonomic classDescription
LKOG2287All organisms (root)beta-1,3-galactosyltransferase 2 [EC:2.4.1.86],hydroxyproline O-galactosyltransferase 2/3/4/5/6 [EC:2.4.1.-],beta-1,3-galactosyltransferase 1 [EC:2.4.1.86]
KOG2287Eukaryota (superkingdom)beta-1,3-galactosyltransferase 2 [EC:2.4.1.86],hydroxyproline O-galactosyltransferase 2/3/4/5/6 [EC:2.4.1.-],beta-1,3-galactosyltransferase 1 [EC:2.4.1.86]
HW75IMetazoa (kingdom)beta-1,3-galactosyltransferase 2 [EC:2.4.1.86],beta-1,3-galactosyltransferase 1 [EC:2.4.1.86],N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149]
93ZEHChordata (phylum)LisH domain-containing protein ARMC9,beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-]
5QVFKSarcopterygii (superclass)LisH domain-containing protein ARMC9,beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-]
8Z6V4Mammalia (class)LisH domain-containing protein ARMC9,beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-]
4RF52Euarchontoglires (superorder)LisH domain-containing protein ARMC9,beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-]
4ZPY3Primates (order)LisH domain-containing protein ARMC9
987XCHaplorrhini (suborder)LisH domain-containing protein ARMC9
BV9AMSimiiformes (infraorder)LisH domain-containing protein ARMC9
9EMYECatarrhini (parvorder)LisH domain-containing protein ARMC9
7MDFAOpisthokonta (clade)beta-1,3-galactosyltransferase 2 [EC:2.4.1.86],beta-1,3-galactosyltransferase 1 [EC:2.4.1.86],N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149]
H658KBilateria (clade)beta-1,3-galactosyltransferase 2 [EC:2.4.1.86],beta-1,3-galactosyltransferase 1 [EC:2.4.1.86],N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149]
9FU8DVertebrata (clade)LisH domain-containing protein ARMC9,beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-]
FX73HHominoidea (superfamily)LisH domain-containing protein ARMC9
5N2S0Hominidae (family)LisH domain-containing protein ARMC9
5Y7IDHomininae (subfamily)LisH domain-containing protein ARMC9

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: