Domains within Homo sapiens protein C1QL2_HUMAN (Q7Z5L3)

Complement C1q-like protein 2

Alternative representations: 1 /

Protein length287 aa
Source databaseUniProt
Identifiers C1QL2_HUMAN, Q7Z5L3, ENSP00000272520.3, ENSP00000272520
Source gene ENSG00000144119

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Chordata

Predicted functional partners

C1QL2_HUMAN is shown as C1QL2 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for C1QL2

Protein C1QL2_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04974Protein digestion and absorption

KEGG orthologous groups

KONameDescription
K06237COL4Acollagen type IV alpha
K19721COL5AScollagen type V/XI/XXIV/XXVII, alpha

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000272520 in eggNOG.

OGTaxonomic classDescription
LKOG3544All organisms (root)collagen type V/XI/XXIV/XXVII, alpha,collagen type IV alpha,C1q-related factor
KOG3544Eukaryota (superkingdom)collagen type V/XI/XXIV/XXVII, alpha,collagen type IV alpha,C1q-related factor
HUTR6Metazoa (kingdom)collagen type V/XI/XXIV/XXVII, alpha,collagen type IV alpha,C1q-related factor
941TDChordata (phylum)collagen type IV alpha,collagen type V/XI/XXIV/XXVII, alpha,C1q-related factor
5QK8NSarcopterygii (superclass)collagen type IV alpha,C1q-related factor,collagen type IX alpha
8ZM6VMammalia (class)C1q-related factor
4RMIBEuarchontoglires (superorder)C1q-related factor
4ZV8PPrimates (order)C1q-related factor
98PRHHaplorrhini (suborder)C1q-related factor
BV317Simiiformes (infraorder)C1q-related factor
9EIXACatarrhini (parvorder)C1q-related factor
H74CUBilateria (clade)collagen type V/XI/XXIV/XXVII, alpha,collagen type IV alpha,C1q-related factor
9GSUVVertebrata (clade)collagen type IV alpha,collagen type V/XI/XXIV/XXVII, alpha,C1q-related factor
7MRKKOpisthokonta (clade)collagen type V/XI/XXIV/XXVII, alpha,collagen type IV alpha,C1q-related factor
FXC4GHominoidea (superfamily)C1q-related factor
5MYU9Hominidae (family)C1q-related factor
5Y8YHHomininae (subfamily)C1q-related factor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: