Domains within Danio rerio protein Q802C7_DANRE (Q802C7)

TAR DNA-binding protein

Alternative representations: 1 /

Protein length412 aa
Source databaseUniProt
Identifiers Q802C7_DANRE, Q802C7, ENSDARP00000058554.5, ENSDARP00000058554
Source gene ENSDARG00000040031

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

Q802C7_DANRE is shown as tardbp in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for tardbp

Protein Q802C7_DANRE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03040Spliceosome
map05014Amyotrophic lateral sclerosis

KEGG orthologous groups

KONameDescription
K12741HNRNPA1_3heterogeneous nuclear ribonucleoprotein A1/A3
K23600TARDBP, TDP43TAR DNA-binding protein 43

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7955.ENSDARP00000058554 in eggNOG.

OGTaxonomic classDescription
9II2NOtomorpha (cohort)TAR DNA-binding protein 43
LKOG0118All organisms (root)heterogeneous nuclear ribonucleoprotein A1/A3,transformer-2 protein,serine/arginine-rich splicing factor 10
KOG0118Eukaryota (superkingdom)heterogeneous nuclear ribonucleoprotein A1/A3,transformer-2 protein,serine/arginine-rich splicing factor 10
HUDCDMetazoa (kingdom)TAR DNA-binding protein 43
93DQHChordata (phylum)TAR DNA-binding protein 43
FXR82Actinopterygii (superclass)TAR DNA-binding protein 43
8NP3SNeopterygii (subclass)TAR DNA-binding protein 43
H6KCNBilateria (clade)TAR DNA-binding protein 43
7NHF9Opisthokonta (clade)TAR DNA-binding protein 43
9G76JVertebrata (clade)TAR DNA-binding protein 43
BETZCCyprinidae (family)TAR DNA-binding protein 43

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: