Domains within Mesocricetus auratus protein Q80Z94_MESAU (Q80Z94)

Gap junction protein

Alternative representations: 1 /

Protein length382 aa
Source databaseUniProt
Identifiers Q80Z94_MESAU, Q80Z94, ENSMAUP00000004854.1, ENSMAUP00000004854, Q8K577_MESAU, Q8K577
Source gene ENSMAUG00000006558

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

Q80Z94_MESAU is shown as Gja1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Gja1

Protein Q80Z94_MESAU is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04540Gap junction

KEGG orthologous groups

KONameDescription
K07612GJA3, CX46gap junction alpha-3 protein
K07372GJA1, CX43gap junction alpha-1 protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10036.ENSMAUP00000004854 in eggNOG.

OGTaxonomic classDescription
6TH14All organisms (root)gap junction alpha-3 protein,gap junction alpha-1 protein,gap junction alpha-4 protein
5EDQ7Eukaryota (superkingdom)gap junction alpha-3 protein,gap junction alpha-1 protein,gap junction alpha-4 protein
HTCKBMetazoa (kingdom)gap junction alpha-1 protein,gap junction alpha-6 protein,cyclin-dependent kinase-like [EC:2.7.11.22]
94HEMChordata (phylum)gap junction alpha-1 protein,gap junction alpha-6 protein,cyclin-dependent kinase-like [EC:2.7.11.22]
5QBGFSarcopterygii (superclass)gap junction alpha-1 protein,gap junction alpha-6 protein,cyclin-dependent kinase-like [EC:2.7.11.22]
8ZB1RMammalia (class)gap junction alpha-1 protein,gap junction alpha-6 protein,cyclin-dependent kinase-like [EC:2.7.11.22]
4R487Euarchontoglires (superorder)gap junction alpha-1 protein,gap junction alpha-6 protein
AI6E1Rodentia (order)gap junction alpha-1 protein,gap junction alpha-6 protein
8DDXYMyomorpha (suborder)gap junction alpha-1 protein
H6A5MBilateria (clade)gap junction alpha-1 protein,gap junction alpha-6 protein,cyclin-dependent kinase-like [EC:2.7.11.22]
7H3SBOpisthokonta (clade)gap junction alpha-1 protein,gap junction alpha-4 protein,gap junction alpha-6 protein
9GJCGVertebrata (clade)gap junction alpha-1 protein,gap junction alpha-6 protein,cyclin-dependent kinase-like [EC:2.7.11.22]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: