Domains within Homo sapiens protein AN13B_HUMAN (Q86YJ7)

Ankyrin repeat domain-containing protein 13B

Alternative representations: 1 /

Protein length626 aa
Source databaseUniProt
Identifiers AN13B_HUMAN, Q86YJ7, ENSP00000378328.3, ENSP00000378328, ENSP00000431958.1, ENSP00000431958, ENSP00000481530.1, ENSP00000481530, Q8N7S9, A0A024QZ29_HUMAN, A0A024QZ29, Q86YJ7-2
Source gene ENSG00000198720
Alternative splicing K7ENT0_HUMAN, AN13B_HUMAN, K7EKP0_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

AN13B_HUMAN is shown as ANKRD13B in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ANKRD13B

Protein AN13B_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04810Regulation of actin cytoskeleton

KEGG orthologous groups

KONameDescription
K21437ANKRD13ankyrin repeat domain-containing protein 13

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 9 PTMs annotated in this protein:

PTMCount
Phosphorylation4
Ubiquitination4
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ANKRD13B.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000378328 in eggNOG.

OGTaxonomic classDescription
LKOG0522All organisms (root)ankyrin repeat domain-containing protein 13,protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
KOG0522Eukaryota (superkingdom)ankyrin repeat domain-containing protein 13,protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
HW4YSMetazoa (kingdom)ankyrin repeat domain-containing protein 13
93KZPChordata (phylum)ankyrin repeat domain-containing protein 13
5R4ZZSarcopterygii (superclass)ankyrin repeat domain-containing protein 13
8Z01VMammalia (class)ankyrin repeat domain-containing protein 13
4RMY1Euarchontoglires (superorder)ankyrin repeat domain-containing protein 13
501N8Primates (order)ankyrin repeat domain-containing protein 13
98KQJHaplorrhini (suborder)ankyrin repeat domain-containing protein 13
BV25QSimiiformes (infraorder)ankyrin repeat domain-containing protein 13
9F1R4Catarrhini (parvorder)ankyrin repeat domain-containing protein 13
7H97WOpisthokonta (clade)ankyrin repeat domain-containing protein 13
9G78YVertebrata (clade)ankyrin repeat domain-containing protein 13
H3TT7Bilateria (clade)ankyrin repeat domain-containing protein 13
FX64MHominoidea (superfamily)ankyrin repeat domain-containing protein 13
5N9SJHominidae (family)ankyrin repeat domain-containing protein 13
5Y8U5Homininae (subfamily)ankyrin repeat domain-containing protein 13

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: