Domains within Mus musculus protein AHSA1_MOUSE (Q8BK64)

Activator of 90 kDa heat shock protein ATPase homolog 1

Alternative representations: 1 /

Protein length338 aa
Source databaseUniProt
Identifiers AHSA1_MOUSE, Q8BK64, ENSMUSP00000021425.6, ENSMUSP00000021425, Q8R3E6, A0A1Y7VM19_MOUSE, A0A1Y7VM19
Source gene ENSMUSG00000021037
Alternative splicing ENSMUSP00000152471.1, AHSA1_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

AHSA1_MOUSE is shown as Ahsa1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ahsa1

Protein AHSA1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04971Gastric acid secretion

KEGG orthologous groups

KONameDescription
K04131CHRM3muscarinic acetylcholine receptor M3

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 20 PTMs annotated in this protein:

PTMCount
Phosphorylation11
Ubiquitination5
Nitrosylation2
Acetylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Ahsa1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000021425 in eggNOG.

OGTaxonomic classDescription
LCOG5580All organisms (root)muscarinic acetylcholine receptor M3
KOG2936Eukaryota (superkingdom)muscarinic acetylcholine receptor M3
HV2BMMetazoa (kingdom)muscarinic acetylcholine receptor M3
94IQIChordata (phylum)Aha1_N,AHSA1
5QX85Sarcopterygii (superclass)Aha1_N,AHSA1
8Z8QBMammalia (class)Aha1_N,AHSA1
4RCPWEuarchontoglires (superorder)Aha1_N,AHSA1
AICXTRodentia (order)Aha1_N,AHSA1
8D4Y9Myomorpha (suborder)Aha1_N,AHSA1
7HCPWOpisthokonta (clade)muscarinic acetylcholine receptor M3
9G8GUVertebrata (clade)Aha1_N,AHSA1
H61MCBilateria (clade)muscarinic acetylcholine receptor M3
CQ0RMMuridae (family)Aha1_N,AHSA1
AE8BVMurinae (subfamily)Aha1_N,AHSA1
5PH1NMus (genus)Aha1_N,AHSA1
HECNFMus (subgenus)Aha1_N,AHSA1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: