Domains within Mus musculus protein BBS4_MOUSE (Q8C1Z7)

Bardet-Biedl syndrome 4 protein homolog

Alternative representations: 1 /

Protein length520 aa
Source databaseUniProt
Identifiers BBS4_MOUSE, Q8C1Z7, ENSMUSP00000026265.6, ENSMUSP00000026265, Q3UYF0, Q562E1, Q5EBJ7, Q8CA57, A6H669_MOUSE, A6H669
Source gene ENSMUSG00000025235
Alternative splicing BBS4_MOUSE, A0A1L1SV19_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

BBS4_MOUSE is shown as Bbs4 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Bbs4

Protein BBS4_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05020Prion disease

KEGG orthologous groups

KONameDescription
K23424TMTCprotein O-mannosyl-transferase [EC:2.4.1.-]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000026265 in eggNOG.

OGTaxonomic classDescription
LCOG0457All organisms (root)protein O-mannosyl-transferase [EC:2.4.1.-],kinesin light chain,Ca-activated chloride channel homolog
KOG1124Eukaryota (superkingdom)protein O-mannosyl-transferase [EC:2.4.1.-],5'-nucleotidase [EC:3.1.3.5],Bardet-Biedl syndrome 4 protein
HVZFMMetazoa (kingdom)Bardet-Biedl syndrome 4 protein
93IWXChordata (phylum)Bardet-Biedl syndrome 4 protein
5R58NSarcopterygii (superclass)Bardet-Biedl syndrome 4 protein
8ZIAIMammalia (class)Bardet-Biedl syndrome 4 protein
4R9CYEuarchontoglires (superorder)Bardet-Biedl syndrome 4 protein
AIA4BRodentia (order)Bardet-Biedl syndrome 4 protein
8DK5YMyomorpha (suborder)Bardet-Biedl syndrome 4 protein
H6RXUBilateria (clade)Bardet-Biedl syndrome 4 protein
9FCZHVertebrata (clade)Bardet-Biedl syndrome 4 protein
7JB9IOpisthokonta (clade)Bardet-Biedl syndrome 4 protein
CQ26MMuridae (family)Bardet-Biedl syndrome 4 protein
AECD8Murinae (subfamily)Bardet-Biedl syndrome 4 protein
5PIXIMus (genus)Bardet-Biedl syndrome 4 protein
HE8PBMus (subgenus)Bardet-Biedl syndrome 4 protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: