Domains within Mus musculus protein IL19_MOUSE (Q8CJ70)

Interleukin-19

Alternative representations: 1 /

Protein length176 aa
Source databaseUniProt
Identifiers IL19_MOUSE, Q8CJ70, ENSMUSP00000139406.1, ENSMUSP00000139406, ENSMUSP00000108084.1, ENSMUSP00000108084, ENSMUSP00000016668.6, ENSMUSP00000016668, Q14BK1_MOUSE, Q14BK1, A0A087WST1_MOUSE, A0A087WST1
Source gene ENSMUSG00000016524
Alternative splicing IL19_MOUSE, ENSMUSP00000141175.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

IL19_MOUSE is shown as Il19 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Il19

Protein IL19_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04630JAK-STAT signaling pathway

KEGG orthologous groups

KONameDescription
K05444IL19interleukin 19

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Phosphorylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Il19.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000139406 in eggNOG.

OGTaxonomic classDescription
6YKNFAll organisms (root)interleukin 19
5FA20Eukaryota (superkingdom)interleukin 19
HTGWYMetazoa (kingdom)interleukin 19
93TD8Chordata (phylum)interleukin 19
5QRTBSarcopterygii (superclass)interleukin 19
8ZMTPMammalia (class)interleukin 19
4RIHNEuarchontoglires (superorder)interleukin 19
AI9IDRodentia (order)interleukin 19
8D9KCMyomorpha (suborder)interleukin 19
7JTQGOpisthokonta (clade)interleukin 19
H591MBilateria (clade)interleukin 19
9FKH9Vertebrata (clade)interleukin 19
CQCNDMuridae (family)interleukin 19
AE9R4Murinae (subfamily)interleukin 19
5PK4KMus (genus)interleukin 19
HEFZXMus (subgenus)interleukin 19

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: