Domains within Leptospira interrogans str. FPW1039 protein A0A0F6IGV9_LEPIR (A0A0F6IGV9)

Cyclic diguanylate phosphodiesterase (EAL) domain protein

Alternative representations: 1 /

Protein length572 aa
Source databaseUniProt
Identifiers A0A1N6NPJ4_LEPIR, A0A1N6NPJ4, A0A2H1XDA4_LEPIR, A0A2H1XDA4, M6RSY7_LEPIR, M6RSY7, A0A0E2CXI2_LEPIR, A0A0E2CXI2, A0A1V2ZIJ5_LEPIR, A0A1V2ZIJ5, M6K3P5_LEPIR, M6K3P5, A0A0C5X8G9_LEPIR, A0A0C5X8G9, M6HH16_LEPIR, M6HH16, A0A0F6HA02_LEPIR, A0A0F6HA02, Q8EXH7_LEPIN, Q8EXH7, Q75FK2_LEPIC, Q75FK2, A0A0M4NCS3_LEPIR, A0A0M4NCS3, A0A0F6I506_LEPIR, A0A0F6I506, N1UML3_LEPIR, N1UML3, A0A1X8WPD9_LEPIR, A0A1X8WPD9, M6G6V8_LEPIR, M6G6V8, M3I3D7_LEPIR, M3I3D7, A0A0F6IGV9_LEPIR, A0A0F6IGV9

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

A0A0F6IGV9_LEPIR is shown as LB_235 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for LB_235

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 189518.LB_235 in eggNOG.

OGTaxonomic classDescription
LCOG2197All organisms (root)two-component system, NarL family, invasion response regulator UvrY,two-component system, NarL family, nitrate/nitrite response regulator NarL,two-component system, NarL family, response regulator DesR
LCOG2200All organisms (root)diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],RNase E specificity factor CsrD
COG2200Bacteria (superkingdom)diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],RNase E specificity factor CsrD
COG2197Bacteria (superkingdom)two-component system, NarL family, invasion response regulator UvrY,two-component system, NarL family, nitrate/nitrite response regulator NarL,two-component system, NarL family, response regulator DesR
4VCQ0Spirochaetes (phylum)c-di-GMP phosphodiesterase [EC:3.1.4.52]
EEM94Spirochaetia (class)c-di-GMP phosphodiesterase [EC:3.1.4.52]
GKA5WLeptospiraceae (family)Response_reg,EAL,GGDEF
4Z85KLeptospira (genus)Response_reg,GGDEF,EAL

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: