Domains within Leptospira interrogans serovar Pyrogenes str. L0374 protein M6K4B6_LEPIR (M6K4B6)

AAA ATPase domain protein

Alternative representations: 1 /

Protein length1396 aa
Source databaseUniProt
Identifiers Q8EZ52_LEPIN, Q8EZ52, M6K4B6_LEPIR, M6K4B6

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bacteria

Predicted functional partners

M6K4B6_LEPIR is shown as LA_4008 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for LA_4008

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 189518.LA_4008 in eggNOG.

OGTaxonomic classDescription
LCOG2114All organisms (root)adenylate cyclase [EC:4.6.1.1],guanylate cyclase soluble subunit beta [EC:4.6.1.2],PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
LCOG3899All organisms (root)eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],adenylate cyclase [EC:4.6.1.1],two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
COG2114Bacteria (superkingdom)adenylate cyclase [EC:4.6.1.1],eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],two-component system, sensor histidine kinase ChiS
COG3899Bacteria (superkingdom)eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],adenylate cyclase [EC:4.6.1.1],two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
4V6IWSpirochaetes (phylum)adenylate cyclase [EC:4.6.1.1]
EER54Spirochaetia (class)adenylate cyclase [EC:4.6.1.1]
GK8JGLeptospiraceae (family)adenylate cyclase [EC:4.6.1.1]
4Z4T8Leptospira (genus)adenylate cyclase [EC:4.6.1.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: