Domains within Leptospira interrogans serovar Lai str. 56601 protein Q8F1M0_LEPIN (Q8F1M0)

Serine/threonine kinase with GAF domain

Alternative representations: 1 /

Protein length1731 aa
Source databaseUniProt
Identifiers Q8F1M0_LEPIN, Q8F1M0

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bacteria

Predicted functional partners

Q8F1M0_LEPIN is shown as LA_3113 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for LA_3113

Protein Q8F1M0_LEPIN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05152Tuberculosis
map02025Biofilm formation - Pseudomonas aeruginosa

KEGG orthologous groups

KONameDescription
K12132prkC, stkPeukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
K07315rsbU_Pphosphoserine phosphatase RsbU/P [EC:3.1.3.3]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 189518.LA_3113 in eggNOG.

OGTaxonomic classDescription
LCOG0515All organisms (root)eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],serine/threonine protein kinase, bacterial [EC:2.7.11.1],serine/threonine-protein kinase PknG [EC:2.7.11.1]
LCOG3899All organisms (root)eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],adenylate cyclase [EC:4.6.1.1],two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
LCOG2208All organisms (root)phosphoserine phosphatase RsbU/P [EC:3.1.3.3],two-component system, HptB-dependent secretion and biofilm response regulator,phosphoserine phosphatase RsbX [EC:3.1.3.3]
COG3899Bacteria (superkingdom)eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],adenylate cyclase [EC:4.6.1.1],two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
COG2208Bacteria (superkingdom)phosphoserine phosphatase RsbU/P [EC:3.1.3.3],two-component system, HptB-dependent secretion and biofilm response regulator,phosphoserine phosphatase RsbX [EC:3.1.3.3]
COG0515Bacteria (superkingdom)eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1],serine/threonine protein kinase, bacterial [EC:2.7.11.1],serine/threonine-protein kinase PknG [EC:2.7.11.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: