Domains within Leptospira interrogans serovar Grippotyphosa str. LT2186 protein M3FW94_LEPIR (M3FW94)

Cyclic diguanylate phosphodiesterase (EAL) domain protein

Alternative representations: 1 /

Protein length404 aa
Source databaseUniProt
Identifiers M6G992, M6G992_LEPIR, A0A1N6RVB1_LEPIR, A0A1N6RVB1, M6RBD1_LEPIR, M6RBD1, A0A0F6HDR4_LEPIR, A0A0F6HDR4, M6HDL4_LEPIR, M6HDL4, Q8F2E4_LEPIN, Q8F2E4, Q72T18_LEPIC, Q72T18, M3IRQ3_LEPIT, M3IRQ3, M3DSJ9_LEPIR, M3DSJ9, A0A0M3TM25_LEPIR, A0A0M3TM25, A0A0F6I412_LEPIR, A0A0F6I412, A0A1X8WJN4_LEPIR, A0A1X8WJN4, M6ZDS0_LEPIR, M6ZDS0, M3FW94_LEPIR, M3FW94

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

M3FW94_LEPIR is shown as LA_2827 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for LA_2827

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 189518.LA_2827 in eggNOG.

OGTaxonomic classDescription
LCOG2200All organisms (root)diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],RNase E specificity factor CsrD
LCOG0745All organisms (root)two-component system, OmpR family, response regulator,two-component system, OmpR family, phosphate regulon response regulator PhoB,two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
COG0745Bacteria (superkingdom)two-component system, OmpR family, response regulator,two-component system, OmpR family, phosphate regulon response regulator PhoB,two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
COG2200Bacteria (superkingdom)diguanylate cyclase [EC:2.7.7.65],c-di-GMP phosphodiesterase [EC:3.1.4.52],RNase E specificity factor CsrD
4VBPVSpirochaetes (phylum)EAL,GGDEF,PAS_9
EEQDKSpirochaetia (class)Response_reg,EAL
GK6E1Leptospiraceae (family)Response_reg,EAL
4Z6K7Leptospira (genus)Response_reg,EAL

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: