Domains within Homo sapiens protein SBSPO_HUMAN (Q8IVN8)

Somatomedin-B and thrombospondin type-1 domain-containing protein

Alternative representations: 1 /

Protein length264 aa
Source databaseUniProt
Identifiers SBSPO_HUMAN, Q8IVN8, ENSP00000297354.6, ENSP00000297354, A8KAA5, Q96J64
Source gene ENSG00000164764

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

SBSPO_HUMAN is shown as SBSPON in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SBSPON

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000297354 in eggNOG.

OGTaxonomic classDescription
LCOG0318All organisms (root)long-chain acyl-CoA synthetase [EC:6.2.1.3],fatty-acyl-CoA synthase [EC:6.2.1.-],4-coumarate--CoA ligase [EC:6.2.1.12]
KOG1176Eukaryota (superkingdom)4-coumarate--CoA ligase [EC:6.2.1.12],BR-signaling kinase [EC:2.7.11.1],malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.-]
HTUJ8Metazoa (kingdom)TSP1_spondin,Somatomedin_B,TSP_1
93YDPChordata (phylum)TSP1_spondin,Somatomedin_B,TSP_1
5QXXWSarcopterygii (superclass)TSP1_spondin,Somatomedin_B
8ZFN1Mammalia (class)TSP1_spondin,Somatomedin_B
4RH9VEuarchontoglires (superorder)TSP1_spondin,Somatomedin_B
4ZYGBPrimates (order)TSP1_spondin,Somatomedin_B
98HEEHaplorrhini (suborder)TSP1_spondin,Somatomedin_B
BV5VFSimiiformes (infraorder)TSP1_spondin,Somatomedin_B
9F18SCatarrhini (parvorder)TSP1_spondin,Somatomedin_B
9FNEFVertebrata (clade)TSP1_spondin,Somatomedin_B,TSP_1
H3ZGVBilateria (clade)TSP1_spondin,Somatomedin_B,TSP_1
7K102Opisthokonta (clade)TSP1_spondin,Somatomedin_B,TSP_1
FX6RKHominoidea (superfamily)TSP1_spondin,Somatomedin_B
5N4XVHominidae (family)TSP1_spondin,Somatomedin_B
5Y7HTHomininae (subfamily)TSP1_spondin,Somatomedin_B

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: