Domains within Homo sapiens protein ARI3B_HUMAN (Q8IVW6)

AT-rich interactive domain-containing protein 3B

Alternative representations: 1 /

Protein length561 aa
Source databaseUniProt
Identifiers ARI3B_HUMAN, Q8IVW6, ENSP00000477878.1, ENSP00000477878, O95443, Q59HC9, Q6P9C9
Source gene ENSG00000179361
Alternative splicing Q8IVW6-4, H3BQ92_HUMAN, ARI3B_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

ARI3B_HUMAN is shown as ARID3B in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ARID3B

Protein ARI3B_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05014Amyotrophic lateral sclerosis

KEGG orthologous groups

KONameDescription
K25856ARID3AT-rich interactive domain-containing protein 3

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000477878 in eggNOG.

OGTaxonomic classDescription
LKOG2744All organisms (root)AT-rich interactive domain-containing protein 3,AT-rich interactive domain-containing protein 5,AT-rich interactive domain-containing protein 4B
KOG2744Eukaryota (superkingdom)AT-rich interactive domain-containing protein 3,AT-rich interactive domain-containing protein 5,AT-rich interactive domain-containing protein 4B
HSMUEMetazoa (kingdom)AT-rich interactive domain-containing protein 3,synaptotagmin-4
93XIRChordata (phylum)AT-rich interactive domain-containing protein 3,synaptotagmin-4
5QBPXSarcopterygii (superclass)AT-rich interactive domain-containing protein 3,synaptotagmin-4
8Z2I0Mammalia (class)AT-rich interactive domain-containing protein 3
4RRDKEuarchontoglires (superorder)AT-rich interactive domain-containing protein 3
500HCPrimates (order)AT-rich interactive domain-containing protein 3
98796Haplorrhini (suborder)AT-rich interactive domain-containing protein 3
BV70ISimiiformes (infraorder)AT-rich interactive domain-containing protein 3
9EF93Catarrhini (parvorder)AT-rich interactive domain-containing protein 3
7K6PTOpisthokonta (clade)AT-rich interactive domain-containing protein 3,synaptotagmin-4
H4P3FBilateria (clade)AT-rich interactive domain-containing protein 3,synaptotagmin-4
9FU4NVertebrata (clade)AT-rich interactive domain-containing protein 3,synaptotagmin-4
FXBJHHominoidea (superfamily)AT-rich interactive domain-containing protein 3
5N8R1Hominidae (family)AT-rich interactive domain-containing protein 3
5Y748Homininae (subfamily)AT-rich interactive domain-containing protein 3

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: