Domains within Homo sapiens protein SRBD1_HUMAN (Q8N5C6)

S1 RNA-binding domain-containing protein 1

Alternative representations: 1 /

Protein length995 aa
Source databaseUniProt
Identifiers SRBD1_HUMAN, Q8N5C6, ENSP00000263736.4, ENSP00000263736, Q53T56, Q96TA4, Q9NW11, B7Z6X7_HUMAN, B7Z6X7, Q8N5C6-2
Source gene ENSG00000068784

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

SRBD1_HUMAN is shown as SRBD1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SRBD1

Protein SRBD1_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04112Cell cycle - Caulobacter

KEGG orthologous groups

KONameDescription
K06959texprotein Tex

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 15 PTMs annotated in this protein:

PTMCount
Phosphorylation14
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein SRBD1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000263736 in eggNOG.

OGTaxonomic classDescription
LCOG2183All organisms (root)protein Tex,transcription elongation factor SPT6,competence protein ComEA
KOG1857Eukaryota (superkingdom)HHH_3,Tex_YqgF,Tex_N
HT169Metazoa (kingdom)Tex_YqgF,HHH_3,Tex_N
94G6JChordata (phylum)Tex_YqgF,HHH_3,Tex_N
5R1BGSarcopterygii (superclass)Tex_YqgF,HHH_3,Tex_N
8ZKADMammalia (class)Tex_YqgF,Tex_N,HHH_3
4RG9PEuarchontoglires (superorder)Tex_N,Tex_YqgF,HHH_3
504MIPrimates (order)Tex_N,Tex_YqgF,HHH_3
98PT5Haplorrhini (suborder)Tex_N,Tex_YqgF,HHH_3
BVFC8Simiiformes (infraorder)Tex_N,Tex_YqgF,HHH_3
9EG2WCatarrhini (parvorder)Tex_N,Tex_YqgF,HHH_3
9FJJZVertebrata (clade)Tex_YqgF,HHH_3,Tex_N
7I54AOpisthokonta (clade)Tex_YqgF,HHH_3,Tex_N
H5MV4Bilateria (clade)Tex_YqgF,HHH_3,Tex_N
FXF4VHominoidea (superfamily)Tex_N,Tex_YqgF,HHH_3
5N6R7Hominidae (family)Tex_N,Tex_YqgF,HHH_3
5XYY2Homininae (subfamily)Tex_N,Tex_YqgF,HHH_3

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: