Domains within Homo sapiens protein ANR31_HUMAN (Q8N7Z5)

Putative ankyrin repeat domain-containing protein 31

Alternative representations: 1 /

Protein length1873 aa
Source databaseUniProt
Identifiers ANR31_HUMAN, Q8N7Z5, ENSP00000274361.3, ENSP00000274361
Source gene ENSG00000145700
Alternative splicing D6RJB7_HUMAN, ANR31_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ANR31_HUMAN is shown as ANKRD31 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ANKRD31

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 14 PTMs annotated in this protein:

PTMCount
Phosphorylation11
Acetylation3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ANKRD31.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000274361 in eggNOG.

OGTaxonomic classDescription
LCOG0666All organisms (root)uncharacterized protein,Mce-associated membrane protein,cellulose synthase A [EC:2.4.1.12]
KOG4177Eukaryota (superkingdom)ankyrin,Rab11 family-interacting protein 1/2/5,protein SPT2
HUBG9Metazoa (kingdom)uncharacterized protein
94QBJChordata (phylum)uncharacterized protein
5R4CXSarcopterygii (superclass)Ank_2,Ank,RAMA
8Z26GMammalia (class)Ank_2,Ank,RAMA
4RRQKEuarchontoglires (superorder)Ank_2,Ank,RAMA
4ZQ66Primates (order)Ank,RAMA,Ank_2
98HCZHaplorrhini (suborder)Ank_2,RAMA,Ank
BVB6WSimiiformes (infraorder)Ank,Ank_2,RAMA
9EGHWCatarrhini (parvorder)Ank,Ank_2,RAMA
7K0F2Opisthokonta (clade)ankyrin repeat domain-containing protein 11/12,uncharacterized protein
H4QMJBilateria (clade)uncharacterized protein
9G5QCVertebrata (clade)uncharacterized protein
FX9V5Hominoidea (superfamily)Ank,Ank_2,RAMA
5NA5ZHominidae (family)Ank,Ank_2,RAMA
5Y052Homininae (subfamily)Ank,Ank_2,RAMA

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: