Domains within Encephalitozoon cuniculi GB-M1 protein CTK1_ENCCU (Q8SQW2)

Probable CTD kinase subunit alpha homolog

Alternative representations: 1 /

Protein length329 aa
Source databaseUniProt
Identifiers CTK1_ENCCU, Q8SQW2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

CTK1_ENCCU is shown as CTK1 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CTK1

Protein CTK1_ENCCU is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05132Salmonella infection
map05130Pathogenic Escherichia coli infection

KEGG orthologous groups

KONameDescription
K08819CDK12_13cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
K00916CTK1CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 284813.Q8SQW2 in eggNOG.

OGTaxonomic classDescription
LKOG0600All organisms (root)cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23],CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23],serine/threonine-protein kinase BUR1 [EC:2.7.11.22 2.7.11.23]
KOG0600Eukaryota (superkingdom)cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23],CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23],serine/threonine-protein kinase BUR1 [EC:2.7.11.22 2.7.11.23]
BMB8PFungi (kingdom)CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23],serine/threonine-protein kinase BUR1 [EC:2.7.11.22 2.7.11.23],neural Wiskott-Aldrich syndrome protein
ENIPYMicrosporidia (phylum)Pkinase
DVCN2Apansporoblastina (suborder)Pkinase
7GPHBOpisthokonta (clade)cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23],CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23],serine/threonine-protein kinase BUR1 [EC:2.7.11.22 2.7.11.23]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: