Domains within Homo sapiens protein PO210_HUMAN (Q8TEM1)

Nuclear pore membrane glycoprotein 210

Alternative representations: 1 /

Protein length1887 aa
Source databaseUniProt
Identifiers PO210_HUMAN, Q8TEM1, ENSP00000254508.5, ENSP00000254508, A6NN56, O94980, Q6NXG6, Q8NBJ1, Q9H6C8, Q9UFP3
Source gene ENSG00000132182

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

PO210_HUMAN is shown as NUP210 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for NUP210

Protein PO210_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03013Nucleocytoplasmic transport

KEGG orthologous groups

KONameDescription
K14314NUP210, GP210nuclear pore complex protein Nup210

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 44 PTMs annotated in this protein:

PTMCount
Phosphorylation23
Ubiquitination14
N-linked glycosylation7

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein NUP210.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000254508 in eggNOG.

OGTaxonomic classDescription
LKOG1833All organisms (root)nuclear pore complex protein Nup210,Ras-related protein Rab-13
KOG1833Eukaryota (superkingdom)nuclear pore complex protein Nup210,Ras-related protein Rab-13
HVWIPMetazoa (kingdom)nuclear pore complex protein Nup210,Ras-related protein Rab-13
942TXChordata (phylum)nuclear pore complex protein Nup210,Ras-related protein Rab-13
5R90KSarcopterygii (superclass)nuclear pore complex protein Nup210,Ras-related protein Rab-13
8Z46XMammalia (class)nuclear pore complex protein Nup210,Ras-related protein Rab-13
4R6B0Euarchontoglires (superorder)nuclear pore complex protein Nup210
4ZKJIPrimates (order)nuclear pore complex protein Nup210
98DI8Haplorrhini (suborder)nuclear pore complex protein Nup210
BV3XESimiiformes (infraorder)nuclear pore complex protein Nup210
9EY1MCatarrhini (parvorder)nuclear pore complex protein Nup210
H4VBQBilateria (clade)nuclear pore complex protein Nup210,Ras-related protein Rab-13
9GR6EVertebrata (clade)nuclear pore complex protein Nup210,Ras-related protein Rab-13
7KNCGOpisthokonta (clade)nuclear pore complex protein Nup210,Ras-related protein Rab-13
FWXK5Hominoidea (superfamily)nuclear pore complex protein Nup210
5NE8YHominidae (family)nuclear pore complex protein Nup210
5Y8UMHomininae (subfamily)nuclear pore complex protein Nup210

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: