Domains within Methanopyrus kandleri AV19 protein VATB_METKA (Q8TUT0)

V-type ATP synthase beta chain

Alternative representations: 1 /

Protein length990 aa
Source databaseUniProt
Identifiers VATB_METKA, Q8TUT0

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

VATB_METKA is shown as ntpB in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ntpB

Protein VATB_METKA is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03030DNA replication

KEGG orthologous groups

KONameDescription
K02319polDNA polymerase, archaea type [EC:2.7.7.7] iPath3
K03243EIF5Btranslation initiation factor 5B
K02118ATPVB, ntpB, atpBV/A-type H+/Na+-transporting ATPase subunit B iPath3
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 190192.MK1673 in eggNOG.

OGTaxonomic classDescription
737HVAll organisms (root)DNA polymerase, archaea type [EC:2.7.7.7],replicative DNA helicase Mcm [EC:5.6.2.3],replication factor C small subunit
76YQXAll organisms (root)translation initiation factor 5B,ATP-dependent helicase Lhr and Lhr-like helicase [EC:3.6.4.13 5.6.2.4],reverse gyrase [EC:5.6.2.2 5.6.2.-]
LCOG1156All organisms (root)V/A-type H+/Na+-transporting ATPase subunit B,V-type H+-transporting ATPase subunit B,F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
arCOG00865Archaea (superkingdom)V/A-type H+/Na+-transporting ATPase subunit B,F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1],F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
arCOG03145Archaea (superkingdom)DNA polymerase, archaea type [EC:2.7.7.7],replicative DNA helicase Mcm [EC:5.6.2.3],replication factor C small subunit
arCOG03151Archaea (superkingdom)translation initiation factor 5B,ATP-dependent helicase Lhr and Lhr-like helicase [EC:3.6.4.13 5.6.2.4],reverse gyrase [EC:5.6.2.2 5.6.2.-]
EKFEAEuryarchaeota (phylum)V/A-type H+/Na+-transporting ATPase subunit B,F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: