Domains within Pyrococcus furiosus DSM 3638 protein VATA_PYRFU (Q8U4A6)

V-type ATP synthase alpha chain

Alternative representations: 1 /

Protein length1013 aa
Source databaseUniProt
Identifiers I6TY35_9EURY, I6TY35, VATA_PYRFU, Q8U4A6

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

VATA_PYRFU is shown as atpA in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for atpA

Protein VATA_PYRFU is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03030DNA replication

KEGG orthologous groups

KONameDescription
K02117ATPVA, ntpA, atpAV/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] iPath3
K04801rfcSreplication factor C small subunit
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 186497.PF0182 in eggNOG.

OGTaxonomic classDescription
LCOG1155All organisms (root)V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1],V-type H+-transporting ATPase subunit A [EC:7.1.2.2],lens fiber membrane intrinsic protein
737HYAll organisms (root)replication factor C small subunit,V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1],ATP-dependent helicase Lhr and Lhr-like helicase [EC:3.6.4.13 5.6.2.4]
arCOG00868Archaea (superkingdom)V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
arCOG03154Archaea (superkingdom)replication factor C small subunit,V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1],ATP-dependent helicase Lhr and Lhr-like helicase [EC:3.6.4.13 5.6.2.4]
EM1ABEuryarchaeota (phylum)V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
EFSMUThermococcaceae (family)V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
AJ4K9Pyrococcus (genus)V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: