Domains within Homo sapiens protein CCNB3_HUMAN (Q8WWL7)

G2/mitotic-specific cyclin-B3

Alternative representations: 1 /

Protein length1395 aa
Source databaseUniProt
Identifiers CCNB3_HUMAN, Q8WWL7, ENSP00000365210.1, ENSP00000365210, ENSP00000276014.7, ENSP00000276014, B1AQI5, B1AQI6, Q96SB5, Q96SB6, Q96SB7, Q9NT38
Source gene ENSG00000147082
Alternative splicing CCNB3_HUMAN, ENSP00000365206.1, Q8WWL7-3

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

CCNB3_HUMAN is shown as CCNB3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CCNB3

Protein CCNB3_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04068FoxO signaling pathway
map05170Human immunodeficiency virus 1 infection

KEGG orthologous groups

KONameDescription
K21771CCNB3G2/mitotic-specific cyclin-B3
K21770CCNB2G2/mitotic-specific cyclin-B2
K21777CCNBG2/mitotic-specific cyclin-B, other

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 24 PTMs annotated in this protein:

PTMCount
Phosphorylation18
Acetylation6

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein CCNB3.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000365210 in eggNOG.

OGTaxonomic classDescription
LKOG0653All organisms (root)G2/mitotic-specific cyclin-B, other,G2/mitotic-specific cyclin-B2,cyclin G2
KOG0653Eukaryota (superkingdom)G2/mitotic-specific cyclin-B, other,G2/mitotic-specific cyclin-B2,cyclin G2
HTZSGMetazoa (kingdom)G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin-B3,WD repeat-containing protein 41
942MGChordata (phylum)G2/mitotic-specific cyclin-B3
5R3TUSarcopterygii (superclass)G2/mitotic-specific cyclin-B3
8ZC5EMammalia (class)G2/mitotic-specific cyclin-B3
4R7FMEuarchontoglires (superorder)G2/mitotic-specific cyclin-B3
503M6Primates (order)G2/mitotic-specific cyclin-B3
98I4QHaplorrhini (suborder)G2/mitotic-specific cyclin-B3
BV7DESimiiformes (infraorder)G2/mitotic-specific cyclin-B3
9EYXDCatarrhini (parvorder)G2/mitotic-specific cyclin-B3
9GEBCVertebrata (clade)G2/mitotic-specific cyclin-B3
H67HWBilateria (clade)G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin-B3,G2/mitotic-specific cyclin-B1
7ICZNOpisthokonta (clade)G2/mitotic-specific cyclin-B2,G2/mitotic-specific cyclin-B3,G2/mitotic-specific cyclin 2
FXBB7Hominoidea (superfamily)G2/mitotic-specific cyclin-B3
5MZSFHominidae (family)G2/mitotic-specific cyclin-B3
5Y4U6Homininae (subfamily)G2/mitotic-specific cyclin-B3

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: