Domains within Mus musculus protein SH319_MOUSE (Q91X43)

SH3 domain-containing protein 19

Alternative representations: 1 /

Protein length789 aa
Source databaseUniProt
Identifiers SH319_MOUSE, Q91X43, ENSMUSP00000138320.1, ENSMUSP00000138320, ENSMUSP00000103291.2, ENSMUSP00000103291, O08635, O35146, Q8C7I2, Q91X43-2
Source gene ENSMUSG00000028082

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Euteleostomi

Predicted functional partners

SH319_MOUSE is shown as Sh3d19 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Sh3d19

Protein SH319_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05418Fluid shear stress and atherosclerosis

KEGG orthologous groups

KONameDescription
K23714SH3D19SH3 domain-containing protein 19

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000158775 in eggNOG.

OGTaxonomic classDescription
LKOG4225All organisms (root)SH3 domain-containing protein 19,neutrophil cytosolic factor 2,E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
KOG4225Eukaryota (superkingdom)SH3 domain-containing protein 19,neutrophil cytosolic factor 2,E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
HVV7MMetazoa (kingdom)SH3 domain-containing protein 19
949SSChordata (phylum)SH3 domain-containing protein 19
5QBGMSarcopterygii (superclass)SH3 domain-containing protein 19
8Z4UWMammalia (class)SH3 domain-containing protein 19
4RS07Euarchontoglires (superorder)SH3 domain-containing protein 19
AI3UWRodentia (order)SH3 domain-containing protein 19
8DHUQMyomorpha (suborder)SH3 domain-containing protein 19
H5A6XBilateria (clade)SH3 domain-containing protein 19
9FVWJVertebrata (clade)SH3 domain-containing protein 19
7M1KMOpisthokonta (clade)SH3 domain-containing protein 19
CQ078Muridae (family)SH3 domain-containing protein 19
AE8UNMurinae (subfamily)SH3 domain-containing protein 19
5PS1HMus (genus)SH3 domain-containing protein 19
HEEZIMus (subgenus)SH3 domain-containing protein 19

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: