Domains within Mus musculus protein Q924X4_MOUSE (Q924X4)

Parathyroid hormone-related protein

Alternative representations: 1 /

Protein length175 aa
Source databaseUniProt
Identifiers Q924X4_MOUSE, Q924X4, ENSMUSP00000051433.6, ENSMUSP00000051433, ENSMUSP00000145509.1, ENSMUSP00000145509
Source gene ENSMUSG00000048776

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Amniota

Predicted functional partners

Q924X4_MOUSE is shown as Pthlh in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Pthlh

Protein Q924X4_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04928Parathyroid hormone synthesis, secretion and action

KEGG orthologous groups

KONameDescription
K22608PTHLH, PTHRPparathyroid hormone-related hormone

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000051433 in eggNOG.

OGTaxonomic classDescription
6Z6SPAll organisms (root)parathyroid hormone-related hormone
5EU6GEukaryota (superkingdom)parathyroid hormone-related hormone
HSXTIMetazoa (kingdom)parathyroid hormone-related hormone
93T71Chordata (phylum)parathyroid hormone-related hormone
5QUB4Sarcopterygii (superclass)parathyroid hormone-related hormone
8Z74GMammalia (class)parathyroid hormone-related hormone
4R23BEuarchontoglires (superorder)parathyroid hormone-related hormone
AI333Rodentia (order)parathyroid hormone-related hormone
8DCBQMyomorpha (suborder)parathyroid hormone-related hormone
7NDSYOpisthokonta (clade)parathyroid hormone-related hormone
H41SDBilateria (clade)parathyroid hormone-related hormone
9G879Vertebrata (clade)parathyroid hormone-related hormone

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: