Domains within Homo sapiens protein RORB_HUMAN (Q92753)

Nuclear receptor ROR-beta

Alternative representations: 1 /

Protein length470 aa
Source databaseUniProt
Identifiers RORB_HUMAN, Q92753, ENSP00000379507.2, ENSP00000379507, Q8WX73, A0A1L4FMK7_HUMAN, A0A1L4FMK7, F7GZT4_MACMU, F7GZT4, G7NGC4, G7PSJ8_MACFA, G7PSJ8, A0A2I2Z4J0_GORGO, A0A2I2Z4J0, A0A2K6MF89_RHIBE, A0A2K6MF89, A0A2K6DSR4_MACNE, A0A2K6DSR4, A0A2I3MFE2_PAPAN, A0A2I3MFE2, A0A2K6T5Y1_SAIBB, A0A2K6T5Y1, A0A2K5JIH9_COLAP, A0A2K5JIH9, A0A2K5ZNM2_MANLE, A0A2K5ZNM2
Source gene ENSG00000198963
Alternative splicing Q58EY0_HUMAN, RORB_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Metazoa

Predicted functional partners

RORB_HUMAN is shown as RORB in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RORB

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 39432.ENSSBOP00000015046 in eggNOG.

OGTaxonomic classDescription
LKOG4216All organisms (root)RAR-related orphan receptor beta,RAR-related orphan receptor alpha,RAR-related orphan receptor gamma
KOG4216Eukaryota (superkingdom)RAR-related orphan receptor beta,RAR-related orphan receptor alpha,RAR-related orphan receptor gamma
HSR7EMetazoa (kingdom)RAR-related orphan receptor beta,RAR-related orphan receptor alpha,RAR-related orphan receptor gamma
93TAVChordata (phylum)RAR-related orphan receptor beta,RAR-related orphan receptor alpha,RAR-related orphan receptor gamma
5R4NUSarcopterygii (superclass)RAR-related orphan receptor beta
8ZNZWMammalia (class)RAR-related orphan receptor beta
4RGQDEuarchontoglires (superorder)RAR-related orphan receptor beta
4ZK12Primates (order)RAR-related orphan receptor beta
98G0KHaplorrhini (suborder)RAR-related orphan receptor beta
BV150Simiiformes (infraorder)RAR-related orphan receptor beta
53Y07Platyrrhini (parvorder)RAR-related orphan receptor beta
H3GERBilateria (clade)RAR-related orphan receptor beta,RAR-related orphan receptor alpha,RAR-related orphan receptor gamma
7JBXUOpisthokonta (clade)RAR-related orphan receptor beta,RAR-related orphan receptor alpha,RAR-related orphan receptor gamma
9G4IWVertebrata (clade)RAR-related orphan receptor beta
9ZBUVCebidae (family)RAR-related orphan receptor beta

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: