Domains within Bos taurus protein ENPL_BOVIN (Q95M18)

Endoplasmin

Alternative representations: 1 /

Protein length804 aa
Source databaseUniProt
Identifiers ENPL_BOVIN, Q95M18, ENSBTAP00000004364.4, ENSBTAP00000004364, Q3MHX8, L8IEQ9_9CETA, L8IEQ9
Source gene ENSBTAG00000003362

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ENPL_BOVIN is shown as HSP90B1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for HSP90B1

Protein ENPL_BOVIN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05418Fluid shear stress and atherosclerosis
map04151PI3K-Akt signaling pathway

KEGG orthologous groups

KONameDescription
K09487HSP90B, TRA1heat shock protein 90kDa beta
K04079HSP90A, htpGmolecular chaperone HtpG

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9913.ENSBTAP00000004364 in eggNOG.

OGTaxonomic classDescription
LCOG0326All organisms (root)molecular chaperone HtpG,heat shock protein 90kDa beta,TNF receptor-associated protein 1
KOG0020Eukaryota (superkingdom)heat shock protein 90kDa beta,molecular chaperone HtpG
HTC24Metazoa (kingdom)heat shock protein 90kDa beta
94KWNChordata (phylum)heat shock protein 90kDa beta
5QNN4Sarcopterygii (superclass)heat shock protein 90kDa beta
8Z9Q0Mammalia (class)heat shock protein 90kDa beta
BQICRLaurasiatheria (superorder)heat shock protein 90kDa beta
AXE6YArtiodactyla (order)heat shock protein 90kDa beta
B5ZG5Pecora (infraorder)heat shock protein 90kDa beta
9FHCHVertebrata (clade)heat shock protein 90kDa beta
H435YBilateria (clade)heat shock protein 90kDa beta
7KGRAOpisthokonta (clade)heat shock protein 90kDa beta
7PE87Bovidae (family)heat shock protein 90kDa beta
DB3HQBovinae (subfamily)heat shock protein 90kDa beta
AZWXMBos (genus)heat shock protein 90kDa beta

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: