Domains within Drosophila melanogaster protein Q95RB1_DROME (Q95RB1)

LD46870p

Alternative representations: 1 /

Protein length418 aa
Source databaseUniProt
Identifiers Q95RB1_DROME, Q95RB1, FBPP0078624, Q9VMZ0
Source gene FBgn0037220

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

Q95RB1_DROME is shown as CG14641 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CG14641

Protein Q95RB1_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03040Spliceosome

KEGG orthologous groups

KONameDescription
K12872RBM22, SLT11pre-mRNA-splicing factor RBM22/SLT11

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 14 PTMs annotated in this protein:

PTMCount
Phosphorylation11
Ubiquitination2
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein CG14641.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0078624 in eggNOG.

OGTaxonomic classDescription
FV400melanogaster group (species group)pre-mRNA-splicing factor RBM22/SLT11
LKOG0153All organisms (root)pre-mRNA-splicing factor RBM22/SLT11,peroxisome proliferator-activated receptor gamma coactivator-related protein 1,alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
EIGK6Endopterygota (cohort)pre-mRNA-splicing factor RBM22/SLT11
FDTTPmelanogaster subgroup (species subgroup)pre-mRNA-splicing factor RBM22/SLT11
KOG0153Eukaryota (superkingdom)pre-mRNA-splicing factor RBM22/SLT11,peroxisome proliferator-activated receptor gamma coactivator-related protein 1,alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
HTSF0Metazoa (kingdom)pre-mRNA-splicing factor RBM22/SLT11,histidyl-tRNA synthetase [EC:6.1.1.21],dynactin 4
HIS3JArthropoda (phylum)pre-mRNA-splicing factor RBM22/SLT11
85UWBHexapoda (subphylum)pre-mRNA-splicing factor RBM22/SLT11
AH8FDNeoptera (infraclass)pre-mRNA-splicing factor RBM22/SLT11
ANV3XDiptera (order)pre-mRNA-splicing factor RBM22/SLT11
H6D2FBilateria (clade)pre-mRNA-splicing factor RBM22/SLT11,histidyl-tRNA synthetase [EC:6.1.1.21]
7I6RNOpisthokonta (clade)pre-mRNA-splicing factor RBM22/SLT11,histidyl-tRNA synthetase [EC:6.1.1.21],dynactin 4
EH6D7Drosophila (genus)pre-mRNA-splicing factor RBM22/SLT11
50M1SSophophora (subgenus)pre-mRNA-splicing factor RBM22/SLT11

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: