Domains within Homo sapiens protein SO4A1_HUMAN (Q96BD0)

Solute carrier organic anion transporter family member 4A1

Alternative representations: 1 /

Protein length722 aa
Source databaseUniProt
Identifiers SO4A1_HUMAN, Q96BD0, ENSP00000359538.1, ENSP00000359538, ENSP00000217159.1, ENSP00000217159, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7
Source gene ENSG00000101187
Alternative splicing E1P5H9_HUMAN, SO4A1_HUMAN, ENSP00000414855.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

SO4A1_HUMAN is shown as SLCO4A1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SLCO4A1

Protein SO4A1_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04919Thyroid hormone signaling pathway

KEGG orthologous groups

KONameDescription
K14354SLCO4Asolute carrier organic anion transporter family, member 4A
K14353SLCO3Asolute carrier organic anion transporter family, member 3A

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 14 PTMs annotated in this protein:

PTMCount
Phosphorylation11
Ubiquitination3

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein SLCO4A1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000217159 in eggNOG.

OGTaxonomic classDescription
LKOG3626All organisms (root)solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C
KOG3626Eukaryota (superkingdom)solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C
HUBUPMetazoa (kingdom)solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C
93KEWChordata (phylum)solute carrier organic anion transporter family, member 5A,solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 4C
5QCKZSarcopterygii (superclass)solute carrier organic anion transporter family, member 4C,solute carrier organic anion transporter family, member 5A,solute carrier organic anion transporter family, member 4A
8YZUEMammalia (class)solute carrier organic anion transporter family, member 4C,solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 6A
4RC5EEuarchontoglires (superorder)solute carrier organic anion transporter family, member 4A
4ZVVRPrimates (order)solute carrier organic anion transporter family, member 4A
98BZAHaplorrhini (suborder)solute carrier organic anion transporter family, member 4A
BV1TCSimiiformes (infraorder)solute carrier organic anion transporter family, member 4A
9ERERCatarrhini (parvorder)solute carrier organic anion transporter family, member 4A
H6B1CBilateria (clade)solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C,solute carrier organic anion transporter family, member 4A
9GJGYVertebrata (clade)solute carrier organic anion transporter family, member 5A,solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 4C
7N0JWOpisthokonta (clade)solute carrier organic anion transporter family, member 4A,solute carrier organic anion transporter family, member 3A,solute carrier organic anion transporter family, member 1C
FX4QDHominoidea (superfamily)solute carrier organic anion transporter family, member 4A
5N7AVHominidae (family)solute carrier organic anion transporter family, member 4A
5Y1AQHomininae (subfamily)solute carrier organic anion transporter family, member 4A

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: