Domains within Homo sapiens protein PGRP3_HUMAN (Q96LB9)

Peptidoglycan recognition protein 3

Alternative representations: 1 /

Protein length341 aa
Source databaseUniProt
Identifiers PGRP3_HUMAN, Q96LB9, ENSP00000290722.1, ENSP00000290722, A1A4U8, Q5SY65
Source gene ENSG00000159527

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eutheria

Predicted functional partners

PGRP3_HUMAN is shown as PGLYRP3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for PGLYRP3

Protein PGRP3_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04624Toll and Imd signaling pathway

KEGG orthologous groups

KONameDescription
K01446PGRPpeptidoglycan recognition protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000290722 in eggNOG.

OGTaxonomic classDescription
LCOG5479All organisms (root)peptidoglycan recognition protein,peptidoglycan-recognition protein LB [EC:3.5.1.28],peptidoglycan recognition protein SB [EC:3.5.1.28]
5J0G1Eukaryota (superkingdom)peptidoglycan recognition protein,peptidoglycan-recognition protein LB [EC:3.5.1.28],peptidoglycan recognition protein SB [EC:3.5.1.28]
HUQT6Metazoa (kingdom)peptidoglycan recognition protein,peptidoglycan-recognition protein LB [EC:3.5.1.28],peptidoglycan recognition protein SB [EC:3.5.1.28]
93FFNChordata (phylum)peptidoglycan recognition protein
5QJE8Sarcopterygii (superclass)peptidoglycan recognition protein
8ZK18Mammalia (class)peptidoglycan recognition protein
4RRSIEuarchontoglires (superorder)peptidoglycan recognition protein
4ZP31Primates (order)peptidoglycan recognition protein
98RA4Haplorrhini (suborder)peptidoglycan recognition protein
BV1WRSimiiformes (infraorder)peptidoglycan recognition protein
9EKN0Catarrhini (parvorder)peptidoglycan recognition protein
H3UTIBilateria (clade)peptidoglycan recognition protein,peptidoglycan-recognition protein LB [EC:3.5.1.28],peptidoglycan recognition protein LC
9GBHBVertebrata (clade)peptidoglycan recognition protein
7KXMWOpisthokonta (clade)peptidoglycan recognition protein,peptidoglycan-recognition protein LB [EC:3.5.1.28],peptidoglycan recognition protein SB [EC:3.5.1.28]
FX7SRHominoidea (superfamily)peptidoglycan recognition protein
5N513Hominidae (family)peptidoglycan recognition protein
5Y3GYHomininae (subfamily)peptidoglycan recognition protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: