Domains within Homo sapiens protein NOE1_HUMAN (Q99784)

Noelin

Alternative representations: 1 /

Protein length485 aa
Source databaseUniProt
Identifiers NOE1_HUMAN, Q99784, ENSP00000360858.3, ENSP00000360858, Q8N8R0, Q969S7, Q99452, Q53XZ8, Q6IMJ4, Q6IMJ5, H2R1M0_PANTR, H2R1M0, A0A2J8UIQ0_PONAB, A0A2J8UIQ0, A0A2K6N6S6_RHIBE, A0A2K6N6S6, A0A2K6Q7W9_RHIRO, A0A2K6Q7W9, A0A2K5EZL4_AOTNA, A0A2K5EZL4, A0A2I3LPX1_PAPAN, A0A2I3LPX1, A0A2K5PEP5_CEBCA, A0A2K5PEP5
Source gene ENSG00000130558
Alternative splicing Q6IMJ6_HUMAN, Q6IMJ7_HUMAN, Q6IMJ8_HUMAN, Q5VZL8_HUMAN, F8W870_HUMAN, ENSP00000360861.3, ENSP00000444296.1, ENSP00000376717.4, NOE1_HUMAN, ENSP00000443806.1, H0YFB9_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

NOE1_HUMAN is shown as OLFM1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for OLFM1

Protein NOE1_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04080Neuroactive ligand-receptor interaction

KEGG orthologous groups

KONameDescription
K25448OLFML1_3olfactomedin-like protein 1/3

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000360858 in eggNOG.

OGTaxonomic classDescription
LKOG3545All organisms (root)olfactomedin-like protein 1/3,olfactomedin-like protein 2,olfactomedin-4
KOG3545Eukaryota (superkingdom)olfactomedin-like protein 1/3,olfactomedin-like protein 2,noelin-3
HU7KUMetazoa (kingdom)noelin-3,noelin,noelin-2
94AHQChordata (phylum)noelin-3,noelin-2,noelin
5QC21Sarcopterygii (superclass)noelin-3,noelin-2,noelin
8Z9GNMammalia (class)noelin
4R9JHEuarchontoglires (superorder)noelin
4ZKHAPrimates (order)noelin
9854IHaplorrhini (suborder)noelin
BUYP1Simiiformes (infraorder)noelin
9F0HJCatarrhini (parvorder)noelin
7P1NXOpisthokonta (clade)noelin-3,noelin,noelin-2
H3QVYBilateria (clade)noelin-3,noelin,noelin-2
9GMZWVertebrata (clade)noelin-3,noelin-2,noelin
FXAU6Hominoidea (superfamily)noelin
5N2CTHominidae (family)noelin
5Y8Z5Homininae (subfamily)noelin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: