Domains within Mus musculus protein SNTB1_MOUSE (Q99L88)

Beta-1-syntrophin

Alternative representations: 1 /

Protein length537 aa
Source databaseUniProt
Identifiers SNTB1_MOUSE, Q99L88, ENSMUSP00000041294.5, ENSMUSP00000041294, O35925
Source gene ENSMUSG00000060429
Alternative splicing SNTB1_MOUSE, Q99L88-2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

SNTB1_MOUSE is shown as Sntb1 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Sntb1

Protein SNTB1_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04217Necroptosis

KEGG orthologous groups

KONameDescription
K24064SNTBbeta-syntrophin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 35 PTMs annotated in this protein:

PTMCount
Phosphorylation29
Acetylation4
Methylation1
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Sntb1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000041294 in eggNOG.

OGTaxonomic classDescription
LKOG3551All organisms (root)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
KOG3551Eukaryota (superkingdom)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
HT8IBMetazoa (kingdom)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
94FB1Chordata (phylum)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
5R07WSarcopterygii (superclass)beta-syntrophin,vacuolar protein-sorting-associated protein 4
8Z8K3Mammalia (class)beta-syntrophin
4RIYEEuarchontoglires (superorder)beta-syntrophin
AI95ERodentia (order)beta-syntrophin
8D7Z5Myomorpha (suborder)beta-syntrophin
H4BI7Bilateria (clade)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
7K9HFOpisthokonta (clade)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
9FMRRVertebrata (clade)beta-syntrophin,alpha-syntrophin,vacuolar protein-sorting-associated protein 4
CQ4VRMuridae (family)beta-syntrophin
AE027Murinae (subfamily)beta-syntrophin
5PJHAMus (genus)beta-syntrophin
HECW1Mus (subgenus)beta-syntrophin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: