Domains within Homo sapiens protein SCMC3_HUMAN (Q9BV35)

Calcium-binding mitochondrial carrier protein SCaMC-3

Alternative representations: 1 /

Protein length468 aa
Source databaseUniProt
Identifiers SCMC3_HUMAN, Q9BV35, ENSP00000301454.3, ENSP00000301454, B4DGB6, Q4LBC2, Q705K3, Q86Y43, Q8N2N4, Q96NQ4, K7APP8_PANTR, K7APP8
Source gene ENSG00000125648
Alternative splicing M0R2F3_HUMAN, M0R2I4_HUMAN, M0R1W8_HUMAN, Q9BV35-3, M0QZP9_HUMAN, SCMC3_HUMAN, M0QZT4_HUMAN, M0QZJ5_HUMAN, ENSP00000334537.4, ENSP00000472177.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

SCMC3_HUMAN is shown as SLC25A23 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SLC25A23

Protein SCMC3_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map00520Amino sugar and nucleotide sugar metabolism iPath3
Some of these pathways are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

KEGG orthologous groups

KONameDescription
K14684SLC25A23Ssolute carrier family 25 (mitochondrial adenine nucleotide transporter), member 23/24/25/41

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000301454 in eggNOG.

OGTaxonomic classDescription
LKOG0036All organisms (root)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41,NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2],NAD(P)H-quinone oxidoreductase subunit I [EC:7.1.1.2]
KOG0036Eukaryota (superkingdom)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41,NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2],NAD(P)H-quinone oxidoreductase subunit I [EC:7.1.1.2]
HUMBJMetazoa (kingdom)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41,transcriptional repressor CTCF,UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83]
93K74Chordata (phylum)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41,transcriptional repressor CTCF,UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83]
5QZYHSarcopterygii (superclass)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41,transcriptional repressor CTCF
8YY46Mammalia (class)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41
4R2TCEuarchontoglires (superorder)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41
4ZQR5Primates (order)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41
98PJMHaplorrhini (suborder)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41
BVE04Simiiformes (infraorder)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41
9EQ7CCatarrhini (parvorder)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41
9G1QBVertebrata (clade)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41,transcriptional repressor CTCF,UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83]
7I9P5Opisthokonta (clade)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41,NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2],transcriptional repressor CTCF
H69BIBilateria (clade)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41,transcriptional repressor CTCF,UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83]
FX7UNHominoidea (superfamily)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41
5NCSBHominidae (family)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41
5XW8AHomininae (subfamily)solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: