Domains within Homo sapiens protein KTNB1_HUMAN (Q9BVA0)

Katanin p80 WD40 repeat-containing subunit B1

Alternative representations: 1 /

Protein length655 aa
Source databaseUniProt
Identifiers KTNB1_HUMAN, Q9BVA0, ENSP00000368982.3, ENSP00000368982, A6NCG6, O60620
Source gene ENSG00000140854
Alternative splicing H3BTV8_HUMAN, ENSP00000457046.1, H3BTU7_HUMAN, H3BPD8_HUMAN, KTNB1_HUMAN, ENSP00000455350.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

KTNB1_HUMAN is shown as KATNB1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for KATNB1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 12 PTMs annotated in this protein:

PTMCount
Phosphorylation10
Ubiquitination2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein KATNB1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000368982 in eggNOG.

OGTaxonomic classDescription
LKOG0267All organisms (root)katanin p80 WD40 repeat-containing subunit B1
KOG0267Eukaryota (superkingdom)katanin p80 WD40 repeat-containing subunit B1
HVUYAMetazoa (kingdom)katanin p80 WD40 repeat-containing subunit B1
93PH5Chordata (phylum)katanin p80 WD40 repeat-containing subunit B1
5QH2ASarcopterygii (superclass)katanin p80 WD40 repeat-containing subunit B1
8Z0BEMammalia (class)katanin p80 WD40 repeat-containing subunit B1
4RI5WEuarchontoglires (superorder)katanin p80 WD40 repeat-containing subunit B1
4ZM9QPrimates (order)katanin p80 WD40 repeat-containing subunit B1
98I8IHaplorrhini (suborder)katanin p80 WD40 repeat-containing subunit B1
BVINISimiiformes (infraorder)katanin p80 WD40 repeat-containing subunit B1
9F162Catarrhini (parvorder)katanin p80 WD40 repeat-containing subunit B1
H5TI5Bilateria (clade)katanin p80 WD40 repeat-containing subunit B1
9GU8HVertebrata (clade)katanin p80 WD40 repeat-containing subunit B1
7HH0YOpisthokonta (clade)katanin p80 WD40 repeat-containing subunit B1
FX2KGHominoidea (superfamily)katanin p80 WD40 repeat-containing subunit B1
5N7PYHominidae (family)katanin p80 WD40 repeat-containing subunit B1
5Y7GKHomininae (subfamily)katanin p80 WD40 repeat-containing subunit B1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: