Domains within Homo sapiens protein SALL3_HUMAN (Q9BXA9)

Sal-like protein 3

Alternative representations: 1 /

Protein length1300 aa
Source databaseUniProt
Identifiers SALL3_HUMAN, Q9BXA9, ENSP00000441823.2, ENSP00000441823, ENSP00000478953.1, ENSP00000478953, Q9UGH1, Q9BXA9-4
Source gene ENSG00000256463
Alternative splicing Q9BXA9-2, SALL3_HUMAN, ENSP00000439975.3, I3L3L8_HUMAN, A0A087WXW6_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Fungi/Metazoa group

Predicted functional partners

SALL3_HUMAN is shown as SALL3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SALL3

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 15 PTMs annotated in this protein:

PTMCount
Phosphorylation13
Ubiquitination1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein SALL3.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000441823 in eggNOG.

OGTaxonomic classDescription
LKOG1074All organisms (root)sal-like protein
KOG1074Eukaryota (superkingdom)sal-like protein
HST1WMetazoa (kingdom)sal-like protein
93T2TChordata (phylum)sal-like protein
5QHXBSarcopterygii (superclass)sal-like protein
8YUI5Mammalia (class)sal-like protein
4RS8FEuarchontoglires (superorder)sal-like protein
504F3Primates (order)sal-like protein
98AX1Haplorrhini (suborder)sal-like protein
BVDZ4Simiiformes (infraorder)sal-like protein
9EQYJCatarrhini (parvorder)sal-like protein
7GRRVOpisthokonta (clade)sal-like protein
9G1IUVertebrata (clade)sal-like protein
H6CEBBilateria (clade)sal-like protein
FX7Q1Hominoidea (superfamily)sal-like protein
5NBGGHominidae (family)sal-like protein
5XXRWHomininae (subfamily)sal-like protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: