Domains within Mus musculus protein VASN_MOUSE (Q9CZT5)

Vasorin

Alternative representations: 1 /

Protein length673 aa
Source databaseUniProt
Identifiers VASN_MOUSE, Q9CZT5, ENSMUSP00000045162.3, ENSMUSP00000045162, Q8BJJ0, Q8R2G5
Source gene ENSMUSG00000039646

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Murinae

Predicted functional partners

VASN_MOUSE is shown as Vasn in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Vasn

Protein VASN_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04514Cell adhesion molecules

KEGG orthologous groups

KONameDescription
K22038LRRC8volume-regulated anion channel
K07523LRRC4C, NGL1netrin-G1 ligand
K16351LRRC4, NGL2netrin-G2 ligand

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 9 PTMs annotated in this protein:

PTMCount
Phosphorylation4
N-linked glycosylation3
Ubiquitination2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Vasn.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000045162 in eggNOG.

OGTaxonomic classDescription
LCOG1552All organisms (root)volume-regulated anion channel,leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein,protein phosphatase 1 regulatory subunit 7
KOG0619Eukaryota (superkingdom)volume-regulated anion channel,leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein,leucine-rich repeat transmembrane protein FLRT
HT6CPMetazoa (kingdom)netrin-G1 ligand,netrin-G2 ligand,vasorin
93F0FChordata (phylum)netrin-G1 ligand,netrin-G2 ligand,vasorin
5RA7ZSarcopterygii (superclass)netrin-G1 ligand,netrin-G2 ligand,vasorin
8Z6DKMammalia (class)vasorin,netrin-G3 ligand,netrin-G1 ligand
4R3ZBEuarchontoglires (superorder)vasorin,netrin-G1 ligand,netrin-G3 ligand
AHWSJRodentia (order)vasorin
8DM3GMyomorpha (suborder)vasorin
9FNI5Vertebrata (clade)netrin-G2 ligand,vasorin,netrin-G3 ligand
H6TYVBilateria (clade)netrin-G1 ligand,netrin-G2 ligand,vasorin
7IK4JOpisthokonta (clade)netrin-G1 ligand,netrin-G2 ligand,leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein
CQBC1Muridae (family)vasorin
AE2UQMurinae (subfamily)vasorin
5PWHWMus (genus)vasorin
HEF23Mus (subgenus)vasorin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: