Domains within Danio rerio protein Q9DF41_DANRE (Q9DF41)

BHLH-WRPW transcription factor

Alternative representations: 1 /

Protein length291 aa
Source databaseUniProt
Identifiers Q9DF41_DANRE, Q9DF41, ENSDARP00000073394.3, ENSDARP00000073394, ENSDARP00000151127.1, ENSDARP00000151127, Q6XLP6_DANRE, Q6XLP6
Source gene ENSDARG00000056438

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Coelomata

Predicted functional partners

Q9DF41_DANRE is shown as her9 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for her9

Protein Q9DF41_DANRE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05165Human papillomavirus infection
map05224Breast cancer

KEGG orthologous groups

KONameDescription
K06054HES1hairy and enhancer of split 1
K09087HES2_6_7hairy and enhancer of split 2/6/7

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 11 PTMs annotated in this protein:

PTMCount
Phosphorylation6
Ubiquitination3
Acetylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein her9.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7955.ENSDARP00000073394 in eggNOG.

OGTaxonomic classDescription
9IR3FOtomorpha (cohort)hairy and enhancer of split 1
LKOG4304All organisms (root)hairy and enhancer of split 2/6/7,hairy and enhancer of split related with YRPW motif,hairy and enhancer of split 5
KOG4304Eukaryota (superkingdom)hairy and enhancer of split 2/6/7,hairy and enhancer of split related with YRPW motif,hairy and enhancer of split 5
HUK2CMetazoa (kingdom)hairy and enhancer of split 1,hairy and enhancer of split 2/6/7,hairy and enhancer of split, invertebrate
94AZYChordata (phylum)hairy and enhancer of split 4,hairy and enhancer of split 1
FXJ2PActinopterygii (superclass)hairy and enhancer of split 1
8N419Neopterygii (subclass)hairy and enhancer of split 1
H4401Bilateria (clade)hairy and enhancer of split 1,hairy and enhancer of split, invertebrate,hairy and enhancer of split 2/6/7
7JAACOpisthokonta (clade)hairy and enhancer of split 1,hairy and enhancer of split 2/6/7,hairy and enhancer of split, invertebrate
9G48VVertebrata (clade)hairy and enhancer of split 4,hairy and enhancer of split 1
BEVD4Cyprinidae (family)hairy and enhancer of split 1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: