Domains within Homo sapiens protein WN10A_HUMAN (Q9GZT5)

Protein Wnt-10a

Alternative representations: 1 /

Protein length417 aa
Source databaseUniProt
Identifiers WN10A_HUMAN, Q9GZT5, ENSP00000258411.3, ENSP00000258411, Q53S44, Q96TA7, Q9H7S8, H2QJF8_PANTR, H2QJF8, A0A2K5WE28_MACFA, A0A2K5WE28, A0A2K6N6R4_RHIBE, A0A2K6N6R4, A0A2K5NGW5_CERAT, A0A2K5NGW5, A0A2K6PDT6_RHIRO, A0A2K6PDT6, A0A096NRV9_PAPAN, A0A096NRV9, A0A2K5ZT80_MANLE, A0A2K5ZT80, Q9BTP0_HUMAN, Q9BTP0, Q05BQ6_HUMAN, Q05BQ6
Source gene ENSG00000135925
Alternative splicing WN10A_HUMAN, H7BZB8_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eumetazoa

Predicted functional partners

WN10A_HUMAN is shown as WNT10A in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for WNT10A

Protein WN10A_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05225Hepatocellular carcinoma

KEGG orthologous groups

KONameDescription
K00572WNT7wingless-type MMTV integration site family, member 7
K01357WNT10wingless-type MMTV integration site family, member 10

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000258411 in eggNOG.

OGTaxonomic classDescription
LKOG3913All organisms (root)wingless-type MMTV integration site family, member 7,wingless-type MMTV integration site family, member 2,wingless-type MMTV integration site family, member 5
KOG3913Eukaryota (superkingdom)wingless-type MMTV integration site family, member 7,wingless-type MMTV integration site family, member 2,wingless-type MMTV integration site family, member 5
HUU01Metazoa (kingdom)wingless-type MMTV integration site family, member 10
94GT7Chordata (phylum)wingless-type MMTV integration site family, member 10
5R250Sarcopterygii (superclass)wingless-type MMTV integration site family, member 10
8Z9WVMammalia (class)wingless-type MMTV integration site family, member 10
4RMXUEuarchontoglires (superorder)wingless-type MMTV integration site family, member 10
4ZIXCPrimates (order)wingless-type MMTV integration site family, member 10
989E1Haplorrhini (suborder)wingless-type MMTV integration site family, member 10
BUZFRSimiiformes (infraorder)wingless-type MMTV integration site family, member 10
9EWQRCatarrhini (parvorder)wingless-type MMTV integration site family, member 10
7NEUROpisthokonta (clade)wingless-type MMTV integration site family, member 10
H60Y6Bilateria (clade)wingless-type MMTV integration site family, member 10
9G44WVertebrata (clade)wingless-type MMTV integration site family, member 10
FWZ3QHominoidea (superfamily)wingless-type MMTV integration site family, member 10
5N529Hominidae (family)wingless-type MMTV integration site family, member 10
5XYKTHomininae (subfamily)wingless-type MMTV integration site family, member 10

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: