Domains within Homo sapiens protein ECT2_HUMAN (Q9H8V3)

Protein ECT2

Alternative representations: 1 /

Protein length914 aa
Source databaseUniProt
Identifiers ECT2_HUMAN, Q9H8V3, ENSP00000376457.3, ENSP00000376457, Q0MT80, Q2M269, Q6U836, Q9NSV8, Q9NVW9, Q96SJ9_HUMAN, Q96SJ9, Q96J05_HUMAN, Q96J05, A0A2K6R0T4_RHIRO, A0A2K6R0T4
Source gene ENSG00000114346
Alternative splicing Q9H8V3-4, ECT2_HUMAN, Q9H8V3-2, ENSP00000403501.1, ENSP00000403446.1, ENSP00000412331.1, C9JB41_HUMAN, C9J1C4_HUMAN, ENSP00000389108.1, H7C3G1_HUMAN, H7C103_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Homo sapiens

Predicted functional partners

ECT2_HUMAN is shown as ECT2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ECT2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000376457 in eggNOG.

OGTaxonomic classDescription
LKOG3524All organisms (root)protein ECT2,intersectin,Rho guanine nucleotide exchange factor 17
KOG3524Eukaryota (superkingdom)protein ECT2,intersectin,Rho guanine nucleotide exchange factor 17
HUXW8Metazoa (kingdom)protein ECT2
94DJQChordata (phylum)protein ECT2
5QB2HSarcopterygii (superclass)protein ECT2
8YVW8Mammalia (class)protein ECT2
4R4N2Euarchontoglires (superorder)protein ECT2
503HYPrimates (order)protein ECT2
98IIEHaplorrhini (suborder)protein ECT2
BVCM2Simiiformes (infraorder)protein ECT2
9EKEXCatarrhini (parvorder)protein ECT2
H58BIBilateria (clade)protein ECT2
9G5HMVertebrata (clade)protein ECT2
7J7RPOpisthokonta (clade)protein ECT2
FXCD3Hominoidea (superfamily)protein ECT2
5MZ79Hominidae (family)protein ECT2
5Y345Homininae (subfamily)protein ECT2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: