Domains within Homo sapiens protein ZBT20_HUMAN (Q9HC78)

Zinc finger and BTB domain-containing protein 20

Alternative representations: 1 /

Protein length741 aa
Source databaseUniProt
Identifiers ZBT20_HUMAN, Q9HC78, ENSP00000419153.1, ENSP00000419153, Q63HP6, Q8N6R5, Q9Y410, A0A2J8M3A2_PANTR, A0A2J8M3A2, Q9HC78-2
Source gene ENSG00000181722
Alternative splicing ENSP00000349803.3, ZBT20_HUMAN, C9JCX0_HUMAN, C9JUH0_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Chordata

Predicted functional partners

ZBT20_HUMAN is shown as ZBTB20 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ZBTB20

Protein ZBT20_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05168Herpes simplex virus 1 infection

KEGG orthologous groups

KONameDescription
K09228KRABKRAB domain-containing zinc finger protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000419153 in eggNOG.

OGTaxonomic classDescription
LKOG1721All organisms (root)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
KOG1721Eukaryota (superkingdom)KRAB domain-containing zinc finger protein,SCAN domain-containing zinc finger protein,KRAB and SCAN domains-containing zinc finger protein
HVGKWMetazoa (kingdom)zinc finger and BTB domain-containing protein 20
94T37Chordata (phylum)zinc finger and BTB domain-containing protein 20
5QVFESarcopterygii (superclass)zinc finger and BTB domain-containing protein 20
8Z1SZMammalia (class)zinc finger and BTB domain-containing protein 20
4RDXGEuarchontoglires (superorder)zinc finger and BTB domain-containing protein 20
4ZSBXPrimates (order)zinc finger and BTB domain-containing protein 20
988H1Haplorrhini (suborder)zinc finger and BTB domain-containing protein 20
BV9HFSimiiformes (infraorder)zinc finger and BTB domain-containing protein 20
9F19TCatarrhini (parvorder)zinc finger and BTB domain-containing protein 20
7N1ZEOpisthokonta (clade)zinc finger and BTB domain-containing protein 20
H6GY6Bilateria (clade)zinc finger and BTB domain-containing protein 20
9FAE3Vertebrata (clade)zinc finger and BTB domain-containing protein 20
FXDUIHominoidea (superfamily)zinc finger and BTB domain-containing protein 20
5N3H8Hominidae (family)zinc finger and BTB domain-containing protein 20
5XSHXHomininae (subfamily)zinc finger and BTB domain-containing protein 20

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: