Domains within Vibrio cholerae O1 biovar El Tor str. N16961 protein CQSS_VIBCH (Q9KM66)

CAI-1 autoinducer sensor kinase/phosphatase CqsS

Alternative representations: 1 /

Protein length686 aa
Source databaseUniProt
Identifiers A0A1V9MZM1_VIBCL, A0A1V9MZM1, A0A0X1KZX4_VIBCO, A0A0X1KZX4, C3LVD9_VIBCM, C3LVD9, A0A0H6D0F9_VIBCL, A0A0H6D0F9, A0A0H6FDC8_VIBCL, A0A0H6FDC8, A0A0H3QCH5_VIBCL, A0A0H3QCH5, A0A0H6R984_VIBCL, A0A0H6R984, A0A0K9UPL3_VIBCL, A0A0K9UPL3, CQSS_VIBCH, Q9KM66

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

CQSS_VIBCH is shown as cqsS in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for cqsS

Protein CQSS_VIBCH is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system
map05111Biofilm formation - Vibrio cholerae

KEGG orthologous groups

KONameDescription
K10916cqsStwo-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
K02484K02484two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
K03413cheYtwo-component system, chemotaxis family, chemotaxis protein CheY

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 243277.VC_A0522 in eggNOG.

OGTaxonomic classDescription
LCOG0784All organisms (root)two-component system, chemotaxis family, chemotaxis protein CheY,two-component system, chemotaxis family, chemotaxis protein CheV,two-component system, sensor histidine kinase [EC:2.7.13.3]
LCOG0642All organisms (root)two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3]
COG0784Bacteria (superkingdom)two-component system, chemotaxis family, chemotaxis protein CheY,two-component system, chemotaxis family, chemotaxis protein CheV,two-component system, sensor histidine kinase [EC:2.7.13.3]
COG0642Bacteria (superkingdom)two-component system, OmpR family, sensor kinase [EC:2.7.13.3],two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3],two-component system, sensor histidine kinase [EC:2.7.13.3]
639MXProteobacteria (phylum)two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
ERD7WGammaproteobacteria (class)two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
DS83TVibrionaceae (family)two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
EQHBPVibrio (genus)two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: